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Full Description
Studies on the evolutionary aspects of diet and molecular studies included in this volume indicate that human beings evolved on a diet that was balanced in the essential fatty acids (EFA). In fact, the ratio of omega-6/omega-3 EFA was 1/1 whereas present day diets in both developed and developing countries have a much higher ratio, between 5/1 and 50/1. Additional studies show that a high ratio of omega-6/omega-3 EFA is detrimental to health and may lead to the development of chronic diseases. Improving the dietary ratio by decreasing the omega-6 fatty acids and increasing the omega-3 fatty acids is essential for brain function and for the management of cardiovascular disease, arthritis and cancer. A ratio of 4/1 or less leads to lower dosage and to the reduction of adverse effects of drugs. This volume should be of interest to a large and varied audience of researchers in academia, industry, and government; cardiologists, geneticists, immunologists, neuroscientists, and cancer specialists; as well as nutritionists, dietitians, food scientists, agriculturists, economists and regulators.
Contents
Importance of the Ratio of Omega 6/Omega 3 Essential Fatty Acids - Evolutionary Aspects, Simopoulos, A.P.; The Importance of Omega 6/Omega 3 Fatty Acid Ratio in Cell Function - The Gene Transfer of Omega-3 Fatty Acid Desaturase, Kang, J.X.; Omega 6/Omega 3 Ratio and Brain-Related Functions, Yehuda, S.; Dietary Prevention of Coronary Heart Disease - Focus on Omega 6/Omega 3 Essential Fatty Acid Balance, de Lorgeril, M., Salen, P.; Effects of an Indo-Mediterranean Diet on the Omega 6/Omega 3 Ratio in Patients at High Risk of Coronary Artery Disease - The Indian Paradox, Pella, D., Dubnov, G., Singh, R.B., Sharma, R.; Berry, E.M.; Manor, O.; Omega 6/Omega 3 Fatty Acid Ratio - The Israeli Paradox, Dubnov, G., Berry, E.M.; Linoleic Acid to Alpha-Linolenic Acid Ratio - From Clinical Trials to Inflammatory Markers of Coronary Artery Disease, Zampelas, A., Paschos, G., Rallidis, L., Yiannakouris, N.; The Japan Society for Lipid Nutrition Recommends to Reduce the Intake of Linoleic Acid. A Review and Critique of the Scientific Evidence, Hamazaki, T., Okuyama, H.; Omega 6/Omega 3 Polyunsaturated Fatty Acid Ratio and Cancer, Chaj s, V., Bougnoux, P.; Omega 6/Omega 3 Fatty Acids and Arthritis, Cleland, L.G., James, M.J., Proudman, S.M.
