Migraine : A Neuroinflammatory Disease? (Progress in Inflammation Research)

個数:

Migraine : A Neuroinflammatory Disease? (Progress in Inflammation Research)

  • 提携先の海外書籍取次会社に在庫がございます。通常3週間で発送いたします。
    重要ご説明事項
    1. 納期遅延や、ご入手不能となる場合が若干ございます。
    2. 複数冊ご注文の場合、分割発送となる場合がございます。
    3. 美品のご指定は承りかねます。
  • 【入荷遅延について】
    世界情勢の影響により、海外からお取り寄せとなる洋書・洋古書の入荷が、表示している標準的な納期よりも遅延する場合がございます。
    おそれいりますが、あらかじめご了承くださいますようお願い申し上げます。
  • ◆画像の表紙や帯等は実物とは異なる場合があります。
  • ◆ウェブストアでの洋書販売価格は、弊社店舗等での販売価格とは異なります。
    また、洋書販売価格は、ご注文確定時点での日本円価格となります。
    ご注文確定後に、同じ洋書の販売価格が変動しても、それは反映されません。
  • 製本 Hardcover:ハードカバー版/ページ数 169 p.
  • 言語 ENG
  • 商品コード 9783764362317
  • DDC分類 616.85707

Full Description

This book contains reviews by a renowned group of clinicians and scientists, which consider in great depth the potential involvement of neurogenic inflammation in the pathogenesis of migraine and inhibition of this putative mechanism as a possible mode of action of antimigraine medications. The authors carefully consider current and future potential therapeutic approaches for the abortive as well as preventive treatment of migraine. The pioneering work by Professor Michael A. Moskowitz's group at Harvard gave rise to the "neurogenic hypothesis" of migraine pathogenesis and to an intel- lectual framework for many aspects of migraine research through a detailed phar- macological characterization of the trigeminovascular system. This knowledge then spurred detailed research worldwide into the roles of the dural vasculature, trigem- inal nerve fibers, and sensory neuropeptides, such as substance P and calcitonin gene-related peptide, in migraine.
Similar in-depth investigations have not been made of the role of the seventh cranial parasympathetic nerves but this area war- rants further study because of its potential for interactions with the trigeminovas- cular system and its clear involvement in cluster headache.

Contents

Inflammation in migraine pathogenesis: when, where, and how.- Impact of migraine on a personal and societal level.- Presentation, pathogenesis, and treatment of migraine.- Neurogenic inflammation in the pathogenesis of migraine.- Models of neurogenic inflammation as it relates to migraine.- Mediators and their receptors involved in neurogenic inflammation.- Mast cell involvement in neurogenic inflammation.- Inhibition of neurogenic inflammation in abortive migraine treatment.- Inhibition of neurogenic inflammation in preventive migraine treatment.- Is migraine a neuroinflammatory disease?.