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Full Description
The compound eye of Drosophila is used as a model for human disease and homology to eyes in other taxa. This book covers the major discoveries on the development of the compound eye of Drosophila melanogaster over the last 25 years. These include aspects of the biological mechanisms of pattern formation in the nervous system, the specification of neuronal cell types, unexpected phylogenetic conservation and many new insights into the function of several signal transduction pathways. All chapters in this book have been written by leading experts in this field who have made significant contributions to our understanding of fly eye development.
Contents
Retinal Specification and Determination in Drosophila * Regulators of the Morphogenetic Furrow * NOTCH and the Patterning of Ommatidial Founder Cells in the Developing Drosophila Eye * The Epidermal Growth Factor Receptor in Drosophila Eye Development * Cell Fate Specification in the Drosophila Eye * Tissue Polarity in the Retina * Regulation of Growth and Cell Proliferation During Eye Development * Evolution of Color Vision * Developmental Regulation Through Protein Stability * Programmed Death in Eye Development * Drosophila Compound Eye Morphogenesis: Blind Mechanical Engineers? The Establishment of Retinal Connectivity * Homologies Between Vertebrate and Invertebrate Eyes * Applications of the Drosophila Retina to Human Disease Modeling.