Description
(Short description)
Dieses Handbuch, herausgegeben von zwei Experten auf ihrem Gebiet, zeigt organischen Chemikern, wie die enantioselektive Katalyse zur Darstellung enantiomerenangereicherter Zwischenprodukte im Industriemaßstab genutzt werden kann. Rund 25 Beiträge (unter anderem von Nobelpreisträger W. S. Knowles) stellen verschiedenste enantioselektive Katalysen in intelligent strukturierter, problemorientierter Weise vor-so lassen sich die Ansätze unmittelbar zur Lösung eigener Fragen anwenden und verallgemeinern!
(Table of content)
Asymmetric hydrogenation: The Monsanto L-dopa process
The other l-dopa process
The Chiral Switch of Metolachlor: The Development of a Large Scale Enantioselective Catalytic Process
An Innovative Asymmetric Sulfide Oxidation: The Process Development History behind the New Antiulcer Agent Esomeprazole
Enantioselective Hydrogenation: Towards a Large-Scale Total Synthesis of Chiral Terpenoid Compounds
Comparison of Four Industrial Syntheses of Ethyl (R)-2-Hydroxy-4-Phenylbutyrate
7-Aminocepholasporanic acid - chemical vs. enzymatic production process
Methods for the Biocatalytic Production of L-Amino Acids on Industrial Scale
The large-scale biocatalytic synthesis of enantiopure cyanohydrins
Industrialization Studies on the Jacobsen Hydrolytic Kinetic Resolution of Racemic Epoxides
Scale-up studies in asymmetric transfer hydrogenation
Practical Applications on Biocatalysis or the Manufacturing of Chiral alcohols such as (R)-1,3-butanediol by Stereo-specific Oxidoreduction
Microbial resolution of 2,3-dichloro-1-propanol and 3-chloro-1,2-propanediol
Synthesis of Unnatural Amino Acids
The Application of DuPHOS Rhodium(I) Catalysts for Commercial Scale Asymmetric Hydrogenation
(TMBTP) Ruthenium catalysts: a useful tool for industrial asymmetric hydrogenations
Biocatalytic approaches for large scale production of asymmetric synthons
Master the scale-up of catalytic asymmetric hydrogenations for the manufacture of fine chemicals
Large-Scale Applications of Biocatalysis in the Asymmetric Synthesis of Laboratory Chemicals
Development of an Efficient Synthesis of Chiral 2-Hydroxy Acids
Factors Influencing the Application of Literature Methods Toward the Preparation of a Chiral trans-Cyclopropane Carboxylic Acid Intermediate During Development of a Melatonin Agonist
Hetero Diels-Alder - Biocatalysis Approach for the Synthesis of (S)-3-[2-{(Methylsulfonyl) oxy}ethoxy]-4-(triphenylmethoxy)-1-butanol Methanesulfonate: Successful Application of an Enzyme Resolution Process
Multi kilo resolution of XU305, a key intermediate to the platelet glycoprotein Iib/IIIa receptor antagonist roxifiban via kinetic and dynamic enzymatic resolution
Protease-Catalyzed Preparation of (S)-2-[(tert-Butylsulfonyl)methyl]-hydrocinnamic Acid for Renin Inhibitor RO0425892
Protease-Catalyzed Preparation of Chiral 2-Isobutyl Succinic Acid Derivatives for Collagenase Inhibitor RO0319790
Development of a Biocatalytic Process for the Resolution of (R)- and (S)-Ethyl 3-amino-4-pentynoate Isomers Using Enzyme Penicillin acylase
