がんの免疫療法<br>Cancer Immune Therapy : Experiences and Future Strategies （2002. XXVI, 408 p. w. numerous figs. (some col.). 25 cm）

がんの免疫療法
Cancer Immune Therapy : Experiences and Future Strategies （2002. XXVI, 408 p. w. numerous figs. (some col.). 25 cm）

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  • 製本 Hardcover:ハードカバー版／ページ数 350 p.
  • 商品コード 9783527304417

Full Description


Cure or life with cancer? What can be achieved by cancer immune therapy? The past decade has seen substantial advancements in tumor immunology. Much of the new knowledge has been translated into new strategies for cancer treatment and into clinical trials. Some of these trials herald future breakthroughs, others have been disappointing and have prompted intensive search for alternatives. Major contributors to the field summarize the knowledge on the molecular and cellular mechanisms of tumorigenesis, critically review the instruments of the immune system that might be exploited for therapy, and discuss the clinical experiences with the different immune therapy concepts. Researchers in the fields of immunology, tumor biology and medicine will highly appreciate this up-to-date volume for evaluating future research activities.

Contents

List of Contributors.Color Plates.PART Ifor Universal Tumor--Associated T Cell Epitopes (R. Vonderheide & J. Schultze). Serological Determinants On Tumor Cells (C. Zwick, et al.). Processing and Presentation of Tumor--associated Antigens (P.--M. Kloetzel & A. Sijts). T Cells in Tumor Immunity (P. Romero, et al.). PART II: IMMUNE EVASION AND SUPPRESSION. Major Histocompatibility Complex Modulation and Loss (B. Seliger & U. Ritz). Immune Cells in the Tumor Microenvironment (T. Whiteside). Immunosuppressive Factors in Cancer (R. Bucala & C. Metz). Interleukin--10 in Cancer Immunity (R. Sabat & K. Asadullah). PART III: STRATEGIES FOR CANCER IMMUNOLOGY. Dendritic Cells and Cancer: Prospects for Cancer Vaccination (D. Hart, et al.). The Immune System in Cancer: If It Isn't Broken, Can We Fix It? (R. Vile). Hybrid Cell Vaccination for Cancer Immune Therapy (P. Walden, et al.). Principles and Strategies Employing Heat Shock Proteins for Immunotherapy of Cancers (Z. Li). Applications of CpG Motifs from Bacterial DNA in Cancer Immunotherapy (A. Krieg). The T--Body Approach: Towards Cancer Immuno--Gene Therapy (J. Pinthus & Z. Eshhar). Bone Marrow Transplantation for Immune Therapy (F. Ciceri & C. Bordignon). Immunocytokines: Versatile Molecules for Biotherapy of Malignant Disease (H. Lode, et al.). Immunotoxins and Recombinant Immunotoxins in Cancer Therapy (Y. Reiter & A. Lev).Glossary.Index.