基本説明
Contents: 1. Biology; 2. Epidemiology of Plasma Cell Disorders; 3. Investigations; 4. Treatment; 5. Related Disorders.
Full Description
With contributions from international experts, Myeloma provides a comprehensive overview of multiple myeloma and related plasma-cell disorders. It examines the molecular and biological background of these diseases, as well as their clinical aspects and investigations, and developments in therapy. Containing 150 color illustrations, charts, and graphs, the book summarizes practical applications of cytogenetic studies in plasma-cell dyscrasias, covers the pathology of myeloma bone disease, discusses the current ways of assessing skeletal involvement, and highlights the use of new biophosphonates. This text is a practical reference for hematologists, oncologists, and researchers.
Contents
BIOLOGY Plasma Cells and Immunoglobulins, S. Vincent Rajkumar and P.R. Greipp Molecular Biology of Plasma Cell Disorders, T.H. Landowski and W.S. Dalton The Role of Viruses in the Pathogenesis of Plasma Cell Disorders, K. Tarte and B. Klein Cytokine Abnormalities in Plasma Cell Disorders, N. Raje and K.C. Anderson Cytogenetics in Plasma Cell Disorders, J.R. Sawyer and S. Singhal Immunoregulatory Mechanisms and Immunotherapy, Q. Yi Bone Disease in Myeloma, J.R. Berenson Angiogeneis and Thalidomide in Plasma Cell Disorders, A. Vacca, S. Singhal. D. Ribatti, and F. Dammacco CLINICAL ASPECTS Epidemiology of Plasma Cell Disorders, D.E. Joshua and J. Gibson Clinical Features and Diagnostic Criteria, H. Lokhorst Prognostic Factors in Myeloma, J-L. Harousseau and Phillip Morreau Neuropathy in Plasma Cell Disorders, K.C. Gorson and A.H. Ropper The Kidney in Plasma Cell Disorders, M.J. Shaver-Lewis and S.V. Shah Infections: Principles of Prevention of Therapy, P. Kelleher and H. Chapel INVESTIGATIONS Laboratory Investigations, J.F. Miguel, J. Almeida, and A. Orfao Clinical Significance of Bone Marrow and Bone Morphology in Myeloma, R. Bartl and B. Frisch Imaging Studies, E.J.C. Angtuaco. A. Moulopoulos, T. Hronas, and R. Avva THERAPY Conventional Treatment of Myeloma, A. Zomas and M.A Dimopoulos High-Dose Therapy and Autologous Transplantation, S. Singhal Allogenic Hematopoietic Stem Cell Transplantation in Myeloma, J. Mehta The Role of Radiotherapy, D.C. Shrieve Role of Interferons, B. Sirohi, J. Treleaven, and R. Powles Supportive Therapy, H. Ludwig and E. Fritz OTHER DISEASES Monoclonal Gammopathies of Undetermined Significance, R.A. Kyle and S.V. Rajkumar Solitary Plasmacytoma, J. Mehta and S. Jagannath Amyloides, M.A. Gertz, M.Q. Lacy, and A. Dispenzieri Waldenstrom's Macroglobulinaemia, M.A. Dimopoulos Multicentric Castleman's Disease, G. Frizzera and A. Chadburn Light-Chain Deposition Disease, A.Soloman, D.R. Weiss, and G.A. Herrera
