Full Description
When discussing dementia, the medical literature tends to focus on Alzheimer's disease, leaving other dementias, such as those relating to cerebrovascular disease, somewhat neglected, despite being a common cause of cognitive decline in later life. However, in recent years there has been a remarkable transformation in our knowledge about the role of vascular factors in cognitive decline and dementia. It is now recognized that cerebrovascular disease influences clinical expression of cognitive and non cognitive features in a variety of cognitive disorders, including Alzheimer's disease itself.Cerebrovascular Disease, Cognitive Impairment and Dementia reviews what is now known about the relationship between cerebrovascular disease and dementia. It describes new knowledge of how vascular processes interact with neuro-degenerative ones, and how both appear to be risk factors for the other. The book contains contributions from leading international experts and covers epidemiology, diagnosis, clinical features, investigations (including neuroimaging), management, and service and caregiver issues. The second edition of this pioneering text is completely revised and emphasizes the primary and secondary prevention of cerebrovascular disease and the treatment of cognitive impairment. A truly comprehensive yet accessible text which puts basic research findings in a clinically relevant context, this book will appeal to psychiatrists, neurologists, geriatricians, allied health professionals, and others involved in the care of patients with cognitive impairment and dementia.
Contents
I. CLASSIFICATION AND DIAGNOSIS 1. Historical overview Lars Gustafson 2. Classification and diagnostic criteria Rob Stewart II. EPIDEMIOLOGY AND RISK FACTORS 3. Epidemiology of vascular dementia in Europe Ingmar Skoog and Olafur Aevarsson 4. Epidemiology of vascular dementia in North America John O'Brien and Robin Eastwood 5. Epidemiology of vascular dementia in Japan Akira Homma and Kazuo Hasegawa 6. Epidemiology of vascular dementia in China Yucun Shen and Xin Yu 7 Epidemiology of vascular dementia and vascular cognitive impairment: meta-analysis and risk factors John O'Brien and Anthony Jorm III. PATHOPHYSIOLOGY OF CEREBROVASCULAR DISEASE - WITH REFERENCE TO DEMENTIAS 8. The neuropathology of vascular dementia and its overlap with Alzheimer's disease Arne Brun 9. White matter pathology in vascular dementia Elisabet Englund 10. Neurotransmitter changes in vascular dementia Jenny Court, Elaine Perry and Raj Kalaria 11. Hereditary forms of vascular dementia Martin Dichgans 12. Homocysteine, vascular disease and dementia Marshal Folstein 13. Clinical pathological correlates Lars Gustafson and Ulla Passant IV. CLINICAL FEATURES 14. Vascular mild cognitive impairment and cognitive impairments after stroke Clive Ballard 15. Neuropsychological profile of vascular cognitive impairment and vascular dementia Tammy Scott and Marshal Folstein 16. Non-cognitive features Bob Barker V. ASSESSMENT AND INVESTIGATIONS 17. Clinical assesssment and investigation Alan Thomas 18. Neuroimaging in vascular dementia John O'Brien VI. MANAGEMENT 19. Primary prevention Stephen Davis 20. Secondary prevention: medical management of established cerebrovascular disease Leon Flicker 21. Treatment of cognitive impairment David Wilkinson 22. Management of non-cognitive features David Ames 23. Vascular dementia: consequences for family carers and implications for management Henry Brodaty and Lee-Fay Low 24. The provision of long-term care and the management of behavioural disorders in cerebrovascular disease and dementia Edmond Chiu.
