基本説明
A comprehensive review of all the developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and more.
Full Description
A comprehensive review of all the latest developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and their correlation with the most recent advances in basic science. The authors illuminate the basic electrophysiologic, molecular, and pharmacologic mechanisms underlying ventricular repolarization, relate them to specific disease conditions, and examine the future of antiarrhythmic drug development based on both molecular and electrophysiological properties. They also fully review the clinical presentation and management of specific cardiac repolarization conditions.
Contents
Part I. Introduction
Chapter 1. Ventricular Repolarization and the Identification of the Sudden Death Candidate: Hype or Hope?
Hein J. Wellens and Douglas P. Zipes
Chapter 2. Historical Milestones of Electrical Signal Recording and Analysis
Thorsten Lewalter and Berndt Luderitz
Part II. Basic Electrophysiology, Pharmacology, and Molecular Biology of Ventricular Repolarization
Edited by Charles Antzelevitch
Chapter 3. Physiology and Molecular Biology of Ion Channels Contributing to Ventricular Repolarization
Jeanne M. Nerbonne and Robert S. Kass
Chapter 4. Electrophysiology and Pharmacology of Ventricular Repolarization
Charles Antzelevitch, Andrew C. Zygmunt, and Robert Dumaine
Chapter 5. How Do We Measure Repolarization inside the Heart?
Charles Antzelevitch, Andrew C. Zygmunt, Jeffrey Fish, Guillermo Perez, and Fabiana Scornik
Chapter 6. Contribution of Electrical Heterogeneity of Repolarization to the ECG
Charles Antzelevitch and Vladislav V. Nesterenko
Chapter 7. Electrical and Structural Remodeling of the Ventricular Myocardium in Disease
Antonis A. Armoundas and Gordon F. Tomaselli
Chapter 8. Ischemia-Related Changes in Repolarization
André G. Kléber and Michiel J. Janse
Chapter 9. The Long QT Syndrome: Molecular and Genetic Aspects
Carlo Napolitano and Silvia G. Priori
Chapter 10. Ion Channel Disease as a Cause of the Brugada Syndrome: Molecular and Genetic Aspects
Connie R. Bezzina and Arthur A. M. Wilde
Chapter 11. Cellular and Ionic Mechanisms Underlying Arrhythmogenesis
Charles Antzelevitch, Alexander Burashnikov, and Jose Di Diego
Part III. Clinical Physiology and Pathophysiology of Ventricular Repolarization: Theory and Practice
Edited by Steven C. Hammill, Win K-Kuang Shen, and Ihor Gussak
Chapter12. Evaluation of VentricularRepolarization: The Clinician's Perspective
Jan Nemec, Steven C. Hammill, and Win-Kuang Shen
Chapter 13. Human Cardiac Repolarization
Philip T. Sager
Chapter 14. QT interval and Its Drug-Induced Prolongation
Wojciech Zareba and Arthur J. Moss
Chapter 15. Neuro-Mediated Repolarization Abnormalities
Philippe Coumel and Pierre Maison-Blanche
Chapter 16. The Electrophysiologic Matrix: Equilibrium and Arnsdorf's Paradox
Morton F. Arnsdorf
Chapter 17. Antiarrhythmic Drugs and Future Direction
Arshad Jahangir, Andre Terzic, and Win-Kuan Shen
Part IV. Specific Electrocardiographic Phenomena and Clinical Syndromes of Ventricular Repolarization
Edited by Ihor Gussak, Charles Antzelevitch, and Preben Bjerregaard
Chapter 18. ECG Phenomena of the Early Ventricular Repolarization: Early Repolarization Syndrome
Ihor Gussak, Charles Antzelevitch, and Preben Bjerregaard
Chapter 19. The Brugada Syndrome
Pedro Brugada, Ramon Brugada, Charles Antzelevitch, Koonlawee Nademanee, Jeffrey Towbin, and Josep Brugada
Chapter 20. Clinical Evaluation, Risk Stratification, and Management of Congenital Long QT Syndrome
Anant Khositseth and Michael J. Ackerman
Chapter 21. Prolonged Repolarization and Sudden Infant Death Syndrome
Peter J. Schwartz
Chapter 22. Short QT Interval: ECG Phenomenon and Clinical Syndrome, Ihor Gussak, Charles Antzelevitch
Daniel Goodman, and Preben Bjerregaard
Chapter 23. T-Wave Alterans: Mechanisms, Relevance, and Clinical Implications
Etienne Pruvot and David S. Rosenbaum. Index.
