Full Description
A review and analysis of research and investigations from the perspective of the host intestinal epithelial cell. * Examines the effects of enteric microbial pathogens on host intestinal epithelial cell function and physiology, as well as the signaling events responsible for these functional consequences. * Covers the normal structure and function of the gastrointestinal tract is covered and focuses on specific microbial pathogens. * Examines the results of studies utilizing nonintestinal cell models within the context of findings obtained from model intestinal epithelial systems. * Emphasizes relevant physiological endpoints. This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
Table of Contents1. Functional Morphology of the Intestinal Mucosae: from Crypts to Tips, Jerrold R. Turner 2. Role of the Intestinal M Cells in Microbial Pathogenesis, Marian R. Neutra, Philippe Sansonetti, and Jean-Pierre Kraehenbuhl 3. Intestinal Immunity, Iris Dotan and Lloyd Mayer 4. Cytokines and Epithelial Function, Sean P. Colgan, Glenn T. Guruta, and Cormac T. Taylor 5. Role of Toll-Like Receptors in Innate Immunity of the Intestine, Elke Cario and Daniel K. Podolsky 6. Intestinal IgA: Role in Host Defense, Jiri Mestecky and Michael W. Russell 7. Sequence-Based Methods for Investigating Intestinal Microbes, David N. Fredericks 8. Application of Microarray Analysis to the Investigation of Host-Pathogen Interactions, Dawn A. Israel and Richard M. Peek, Jr. 9. Pathogen-Initiated Inflammatory Response in Intestinal Epithelial Cells: Crosstalk with Neutrophils, Andrew T. Gewirtz, Shanti V. Sitaraman, Didier Merlin, and James L. Madara 10. Upregulation of Innate Defense Mechanisms by Enteric Infections, Martin F. Kagnoff 11. Microbial Interference with Host Inflammatory Responses, Andrew S. Neish 12. Antimicrobial Peptide Effectors of Small Intestinal Innate Immunity, Andre J. Ouellette and Michael E. Selsted 13. Role of Commensal Enteric Bacteria in Intestinal Inflammation: Lessons from Animal Models, R. Balfour Sartor 14. Physiological Regulation of Gastrointestinal Ion Transport, Kim E. Barrett and Lone S. Bertelsen 15. Epithelial Response to Enteric Pathogens: Activation of Chloride Secretory Pathways, V.K. Viswanathan and Gail Hecht 16. Enteric Pathogens That Affect Intestinal Epithelial Tight Junctions, Gail Hecht 17. Enteric Microbial Toxins and the Intestinal Epithelial Cytoskeleton, James P. Nataro, Cynthia Sears, Alessio Fasano, and Robert J. Bloch 18. Ontogeny of the Host Response to Enteric Microbial Infection, Bobby J. Cherayil and W. Allan Walker 19. Neuroimmune Interactions and Pathogenesis of Intestinal Inflammation in Infectious Diseases, Charalabos Pothoulakis 20. Apoptosis and Enteric Bacterial Infections, Barbel Raupach and Arturo Zychlinksy 21. Trafficing of Cholera Toxin and Related Bacterial Pathogens, Catherine A. Lee 22. Type III Secretion Systems of Enteric Bacterial Pathogens, Catherine A. Lee 23. How Noninvasive Pathogens Induce Disease: Lessons from Enteropathogenic and Enterohemorrhagic Escherichia coli, Bruce A. Vallance, Crystal Chan, and B. Brett Finlay 24. Salmonella: Masters of Inflammation, Beth A. McCormick 25. Effector Molecules of Shigella Pathogenesis and Host Responses, M. Isabel Fernandez and Philippe J. Sansonetti 26. Toxins of Vibrio cholerae: Consensus and Controversy, Karla Jean Fullner 27. Pathogenicity of Clostridium difficile Toxins, Michel Warny and Ciaran P. Kelly 28. Viral Pathogens of the Intestine, Mary K. Estes and Robert L. Atmar
