基本説明
Covers the full range of human encephalitis/encephalopathy, including HIV/AIDS, prion diseases, and smallpox.
Full Description
Designed to assist clinicians in the diagnosis and therapy of patients with suspected viral encephalitis. * Presents information according to the clinical and epidemiological information available at the time of presentation of the patients rather than according to principles of viral taxonomy. * Emphasizes neuropathological descriptions and pathogenesis concepts, reflecting the authors' belief that an understanding of pathogenesis facilitates the diagnostic process and is central to therapeutic intervention. * Covers the full range of human encephalitis/encephalopathy, including HIV/AIDS, prion diseases, and smallpox. This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
Table of ContentsPrefaceAcknowledgementsSection I. Introduction1. Pathological Features of Encephalitis in HumansSources of Information on the Pathology of Encephalitis Naked-Eye Examination of the Brain and Routine Light Microscopy Immunocytochemistry, PCR, and In Situ Hybridization Electron Microscopy Pathological Features Common to Most Forms of Viral Encephalitis Pathological Features Restricted to Certain Forms of Encephalitis Mode of Entry of Viruses into the Nervous System Selective Vulnerability of Cells of the Central Nervous System Tempo of the Disease Process Role of the Immune Response Complications and Sequelae The Need for Autopsies2. Diagnostic EvaluationDifferentiation of Encephalitis from Other Conditions Types of Encephalitis: Key Initial Questions Clinical Classification of Encephalitis Diagnostic Evaluation of Encephalitis Diagnostic Virology and Serology Encephalitis of Undetermined Etiology3. Management Decisions in Acute EncephalitisCommon Management Issues Antiviral and Immunomodulating Therapies Therapy by Type of Encephalitis Clinical Evaluation for Acute Management Acute Management Decisions Reduction of Raised Intracranial Pressure Control of Seizures Management in the Recovery PeriodAppendix: Encephalitis Treatment Checklist Arranged by Clinical ClassificationSection II. Acute Sporadic Encephalitis4. Herpes Simplex EncephalitisIntroduction and Classification HSV Historical Considerations Pathology of HSE Pathology of Atypical HSV-1 Encephalitis and HSV-2 Encephalitis and Myelitis Pathogenesis of HSE Clinical Evaluation of HSE Therapy, Course, and Outcomes Recurrent Encephalitis Neonatal Nerpes Simplex Infection5. Systemic Viral Diseases and EncephalitisExanthematous Diseases Mumps Epstein-Barr Virus--Infectious Mononucleosis--Glandular Fever Adenovirus Gastroenteritis-Rotaviruses Hepatitis Viruses6. Encephalitis Viruses Transmitted from AnimalsSporadic Arbovirus Infections Lymphocytic Choriomeningitis Virus Rabies Herpes B Virus of Monkey--Herpesvirus simiae--Cercopithecine HerpesvirusSection III. Acute Parainfectious Immune-Mediated Encephalomyelitis7. Pathology of Allergic Forms of EncephalomyelitisPathology of Human Perivenous Encephalitis Pathology of Acute Hemorrhagic Leukoencephalitis Acute Parainfectious Encephalopathy Pathogenesis of Allergic Encephalitis8. Clinical Syndromes Including Smallpox and MeaslesADEM Acute Cerebellar Ataxia and Related Syndromes Brain Stem ADEM, Including Bickenstaff's Brain Stem Encephalitis Miller Fisher Syndrome Acute Transverse Myelitis Acute Hemorrhagic Leukoencephalopathy (Hurst) Acute Encephalopathy, Including Reye's Syndrome Postviral Stroke Smallpox and Its Vaccination Measles9. Varicella-Zoster Virus: the Paradox of Immune Mediation and ImmunocompromiseChicken Pox ZosterSection IV. Acute Epidemic Encephalitis10. Influenza Virus, Enteroviruses, and Other Epidemic VirusesHuman-to-Human Transmission Animal-to-Human Transmission: Nipah Virus Unknown Means of Transmission11. The ArbovirusesPathology Pathogenesis Diagnosis and Management Mosquito-Borne Encephalitides Tick-Borne EncephalitidesSection V. Subacute and Chronic Encephalitis and Prion Diseases12. HIV/AIDSThe Pathogenesis and Pathology of AIDS Systemic Pathology of AIDS Neuropathology of HIV Infection Pre-AIDS Neuropathology in Untreated Individuals: Lymphocytic Meningitis AIDS Neuropathology Neuronal Pathology and Its Pathogenesis Vascular Pathology AIDS-Associated Myelopathy and HIV Myelitis Influence of Antiretroviral Treatment on the Neuropathology of AIDS Clinical Features of Early HIV Disease in the CNS Antiretroviral Therapy Clinical Features of AIDS in the CNS Pediatric AIDS13. Encephalitis in Immunocompromised PatientsPML CMV Encephalitis and Radiculomyelitis Enteroviral CNS Infections in Primary Hypogammaglobulinemia or Agammaglobulinemia IME Encephalitis Associated with Organ Transplantation and Bone Marrow Allografting14. Encephalitis in Immunocompetent PatientsSSPE PRP HAM/TSP Rasmussen's Encephalitis Vilyuisk Encephalitis--Bokhoror Borna Disease15. Creutzfeldt-Jakob Disease and Other Prion DisordersPathology Pathogenesis of CJD Diagnosis and Management Infection ControlIndex
