Full Description
Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumour-specific therapeutics. Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium. This volume summarizes advances in ovarian cancer detection and treatment and provides an analysis of research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.
Contents
Contributors. Foreword. IDetection of Epithelial Ovarian Cancer; D.A. Fishman, K. Bozorgi. 2. Risk Assessment and Genetic Testing; P.O. Chappuis, W.D. Foulkes. 3. Early Detection of Ovarian Cancer: Promise and Reality; R.C. Bast, Jr., et al. 4. Current Diagnosis and Treatment Modalities for Ovarian Cancer; P.E. Schwartz. 5. Ultrasound and Ovarian Cancer; L. Cohen, D.A. Fishman. 6. Gene Therapy; W.K. Huh, et al. II: Research. A: Malignant Transformation. 7. Normal Ovarian Surface Epithelium; A.S.T. Wong, N. Auersperg. 8. Cytopathology of the Ovary; D.V.S. DeFrias, et al. 9. Telomerase and Malignant Transformation; Jiamei Yu, L. Dubeau. 10. Homeobox Gene Expression in Ovarian Cancer; S.M. Pando, H.S. Taylor. B: Growth Control. 11. EGF/ErbB Receptor Family in Ovarian Cancer; N.J. Maihle, et al. 12. Critical Role of Lysophospholipids in the Pathophysiology, Diagnosis, and Management of Ovarian Cancer; G.B. Mills, et al. 13. Expression of CSF-1 and Its Receptor CSF-1R in Non-Hematopoietic Neoplasms; B. Kascinski. C: Cellular Regulation and Metastasis. 15. Adhesion Molecules; A.P.N. Skubitz. 16. Ovarian Cancer-Associated Proteinases; S. Ghosh, et al. 17. Angiogenesis and Metastasis; G.J. Sieczkiewicz, et al. Index.
