Full Description
Discover effective, outcome-oriented ways to help CFS patients who have endured useless or inappropriate treatments!
From the author: For many years I have viewed brain function as a system of electrochemical impulses continually flashing through the brain. These neural networks can often be modulated fairly simply by 'tuning' them. The point I have been trying to make for many years is that this process may be pharmacologically regulated extremely rapidly in a manner which does not yet seem to be recognized by the medical profession.
In this remarkable volume, Dr. Jay A. Goldstein clearly presents both the theoretical and the practical aspects of his revolutionary approach to treating CFS and other conditions that have often been termed psychosomatic. Dr. Goldstein (author of Chronic Fatigue Syndromes: The Limbic Hypothesis and Betrayal by the Brain: The Neurologic Basis of Chronic Fatigue Syndrome, Fibromyalgia Syndrome, and Related Neural Network Disorders) shows how he achieves results for patients with CFS and a variety of other syndromes in days, rather than months or years.
This well-referenced book answers questions, from the most basic to the most complex, including:
What is neurosomatic medicine?
How did Dr. Goldstein come to pioneer and practice this specialty?
What abnormalities in brain function produce neurosomatic disorders?
How can an understanding of these abnormalities help you provide effective treatment?
Why do these treatments sometimes work so rapidly?
What is receptor profiling, and how does it indicate the type of receptor dysregulation in an individual patient?
In Part I: Inventing Neurosomatic Medicine, Dr. Goldstein describes the remarkable how and why of his life and his development of this new field of medicine, including his clashes with the medical/psychoanalytic establishment. One of the greatest medical innovators of the modern era, Dr. Goldstein has seen over 20,000 CFS patients and has experienced most of the pitfalls that having such a large number of patients entails. He shares his insight on legal issues, such as how to deal with the law and court systems, how to best provide expert testimony, and how to defend against spurious legal actions. In addition, Dr. Goldstein describes how he learned to work effectively outside of the managed care system.
In Part II: Society for Neuroscience Conference Proceedings, the author shares his expertise to bring you experimental results and pearls of wisdom relating to neurosomatic medicine from the 28th and 29th Annual Meetings of the Society for Neurosciencethe largest and most important neuroscience conference in the world. Dr. Goldstein sorted through thousands of experiments presented at the conferences to bring you the most relevant findings.
Part III: Pathophysiology and Treatment is essential reading for anyone planning to practice neurosomatic medicine. In this section, richly illustrated with over 70 pages of color figures and diagrams that make complicated concepts clear, Dr. Goldstein shares his knowledge about dozens of the agents he uses to help CFS sufferers and others manage their pain, fatigue, and other symptoms. This is information that simply cannot be found anywhere else, and will prove invaluable to all fledgling neurosomatic practitioners.
This one-of-a-kind volume is thoughtfully put togetherfrom the extensive list of abbreviations near the beginning to the exhaustive references and an appendix with diagnostic criteria, a treatment algorithm, a medication list of treatment options available now or in the near future, and a checklist of CFS symptoms.
Contents
Foreword
Preface
Abbreviations
Part I: Inventing Neurosomatic Medicine: Rewards and Satisfactions versus Problems and Pitfalls
Chapter 1. The Education of a Neurosomaticist
Chapter 2. The Office Practice of Neurosomatic Medicine
Bankruptcy Despite a Three-Month Waiting List
Solving the Problems and Avoiding the Pitfalls
Taking Care of Business
Chapter 3. Lawyers and Litigation
Sample Pathophysiology of Posttraumatic Fibromyalgia
Mene, Mene, Tekel, Upharsin
Chapter 4. Treatment Case Examples
Instantaneous Neural Network Reconfiguration by Pharmacologic Modulation of Afferent Cranial Nerve Input
The Pathophysiology of CFS and Related Neurosomatic Disorders
Thyroid Function in Neurosomatic Disorders: Stimulation of Trigeminal Nerve Activity with Thyrotropin-Releasing Hormone (TRH)
Chapter 5. Case Reports
My So-Called Illness: Is It Real or All in My Head?
One-Second Epiphanies
My Most Unusual Case
Bug-of-the-Month Club
Chapter 6. Married to a Doctor Who Is Married to His Practice
Part II: Society for Neuroscience Conference Proceedings
Chapter 7. This Is . . . Los Angeles
Chapter 8. Neurosomatic Pearls
Eldritch Lore About Neurosomatic Therapy
Chapter 9. Neurosomatic Neuroscience
Part III: Pathophysiology and Treatment
Chapter 10. Treatment of Neurosomatic Disorders
Abecarnil and Acamprosate
Stimulants
The Corticostriatal-Thalamocortical (CSTC) Circuit in Reverse
Corticotropin-Releasing Hormone (CRH) and Hypocortisolism
Agmatine
Cholinesterase Inhibitors
Ascorbate (Vitamin C)
Amantadine
Adenosine
Baclofen
Gamma-Aminobutyric Acid (GABA)
Adenosine Triphosphate (ATP)
Lorazepam Nasal Spray
Antibiotics
Endothelin (ET)
Respiratory Rhythm Regulation in Fibromyalgia Syndrome
pH and Panic Disorder
Buspirone/BuSpar
Thalamic Reticular Nucleus
The Attentional Network
Clonidine
Catecholamines
Norepinephrine, Dopamine, Salience, and Attention
Dopamine and Reward
Effexor (Venlafaxine)
Synaptic Plasticity and Long-Term Potentiation in Neurosomatic Disorders
The Postreceptor Phosphorylation Cascade
The Treatment of Attentional Disorders
Instantaneous Neural Network Reconfiguration
Other Aspects of Synaptic Plasticity
Hormonal Modulation in Neurosomatic Medicine
Modulating the N-Methyl-D-Aspartate (NMDA) Receptor
Atypical Messengers
Synaptic Fatigue
Glutamate Receptors, Subunits, and Synaptic Scaling
Neurotrophic Factors
Metabotropic Glutamate Receptors
Conclusion
Chapter 11. Modulating Glutamatergic Neurotransmission
Ketamine
Pharmacologic Modulation of Sensory Integration via the Trigeminal Nerve
Electroconvulsive Therapy (ECT)
Kinases and Phosphatases
The Nicotinic Cholinergic Receptor
Long-Term Potentiation and Depression
Mitogen-Activated Protein Kinases (MAPKs)
Gabapentin
Zolpidem
Lamotrigine
Pentazocine (Talwin)
Oxytocin
Opioids
Oxytocin, Hypothalamic Function, and Circadian Rhythms
Other Effects of Oxytocin
Modafinil (Provigil)
Ventrolateral Preoptic Nucleus (VLPO)
Lidocaine
Gonadotropin-Releasing Hormone (GnRH) and Dysregulation of Circadian Rhythms
Pyrrolidines
Fatigue
Sleep
Conclusion
Conclusion. Closing the Circuit: The Role of the Nucleus Accumbens in Neurosomatic Disorders
Appendix
Diagnostic Criteria from the DSM-IV-TR
Treatment Algorithm
Medication List: Present and Near-Future Treatment Options for Neurosomatic Disorders
CFS Symptom Checklist
References
Index
