基本説明
ＮＹＵ－Ｂｅｌｌｅｖｕｅ Ｃｈｅｓｔ Ｓｅｒｖｉｃｅの専門家による編集。８年振りの改訂。結核の疫学、分子生物学、免疫学、治療、薬理学、予防について最新情報をまとめた。
Full Description
This comprehensive clinical reference is edited by experts from the NYU-Bellevue Chest Service, which through its influence in tuberculosis care and education has been an integral part of the formation of the entire specialty of pulmonary medicine. The book draws on this extensive experience to present an authoritative account of the history, epidemiology, microbiology, immunology, clinical treatment, pharmacology, and prevention or control of tuberculosis. The book will serve as a definitive reference for specialists in pulmonary medicine, infectious disease, and public health. New to the Second Edition are more concise and focused chapters, new information on molecular biology from the genome project, and updated information especially for the epidemiology section.
Contents
SECTION IEPIDEMIOLOGYThe Writer's Voice: Tuberculosis in the Arts 3Joan Reibman and Thomas LennonGlobal Epidemiology of Tuberculosis 13Donald A. Enarson, Chen-Yuan Chiang, andJohn F. MurrayEpidemiology of Tuberculosis in the United States31C. Robert Horsburgh, Jr., Marisa Moore, andKenneth G. CastroMolecular Epidemiology of Mycobacteriumtuberculosis 47Barun Mathema and Barry N. KreiswirthSECTION II: GENOMICS ANDMICROBIOLOGYComparative Genomics of the Mycobacteriumtuberculosis Complex: Evolutionary Insight andApplications 65Roland Brosch, Sayera Banu, and Stewart T. ColeGenetic Diversity of the Mycobacteriumtuberculosis Complex 75Marcel A. BehrTuberculosis Latency in Humans 85Charles L. DaleyPersistence and Drug Tolerance 101James E. Gomez and John D. McKinneyThe Cell Wall of Mycobacterium tuberculosis 115Dean C. Crick, Patrick J. Brennan, andMichael R. McNeilMycobacterium tuberculosis Virulence: A GeneticAnalysis 135Issar SmithLaboratory Diagnosis 163Bruce A. HannaNovel Approaches to the Rapid Diagnosis ofTuberculosis 177Neil W. SchlugerSECTION III: HOST RESPONSEImmunodiagnosis 185Suman LaalThe Role of the Nramp1 Gene in MycobacterialInfections 193Ellen Buschman, Emil Skamene, and Erwin SchurrPhagocytosis and Toll-Like Receptors inTuberculosis 203Larry S. SchlesingerNitric Oxide in Tuberculosis 215Carl F. Nathan and Sabine EhrtAnimal Models of Tuberculosis 237JoAnne L. Flynn and John ChanCell-Mediated Immune Response 251Timo Ulrichs and Stefan H. E. KaufmannCD1 Response 263Peter A. Sieling and Robert L. ModlinDendritic Cells 269Ralph M. Steinman and Thomas M. MoranCytokine Response in Tuberculosis 285Rany Condos and William N. RomMolecular Mechanisms of HumanImmunodeficiency Virus/Tuberculosis Interactionin the Lung 301Yoshihiko Hoshino, Bindu Raju, and Michael WeidenProgrammed Cell Death in Tuberculosis 309Joseph Keane and Hardy KornfeldSECTION IV: CLINICAL ASPECTSPathology and Insights into Pathogenesis ofTuberculosis 323Jaishree Jagirdar and David ZagzagPulmonary Tuberculosis 345Stuart M. GarayImaging of Thoracic Tuberculous Infections 395Georgeann McGuinness and Ami N. RubinowitzMiliary Tuberculosis 427Stephen K. Baker and Jeffrey GlassrothTuberculosis of the Brain, Meninges, and SpinalCord 445Michael Henry and Robert S. HolzmanOcular Complications 465Dorothy Nahm Friedberg and Monica Lorenzo-LatkanyTuberculosis of the Head and Neck 477Andrew G. Sikora, Stephen G. Rothstein, Kenneth F.Garay, and Ruth SpiegelMycobacterial Lymphadenitis 489Mark F. SloanePleural Tuberculosis 497Stephan L. KamholzCardiovascular Tuberculosis 509June E. S. Abadilla and Albert E. Heurich
