Full Description
This book provides a background of the fundamentals of basic science related to acute coronary syndrome in combination with extensive sections on diagnosis and treatment management. The frequency of ACS is on the rise worldwide, and this timely book covers management through pharmacologic therapy and revascularization. The section on pharmacologic agents includes contributions from the world leaders in cardiovascular drug therapy. Coverage of the recent guidelines for acute coronary syndrome management is included with commentary from Eugene Braunwald. Included in the "Companion" series to Braunwald's "Heart Disease", this book covers the most challenging cardiovascular problem today.
Contents
I. ACS and Clinical Practice 1. From Pre-Infarction Angina to Acute Coronary Syndromes: The History of Unstable Angina 2. The Dimension of the Problem, National and International Statistics, The Cost for the Society 3. An Epidemiological Perspective; Society, Environment, Risk Factors, and Genetic 4. Natural History and Prognosis in Unstable Angina 5. Organization and Structure of the Coronary Care Units in the Years 2000 II. Pathophysiology 6. Pathology of Acute and Stable Coronary Syndromes 7. Molecular Mechanisms of the Acute Coronary Syndromes: The Roles of Inflammation and Immunity 8. Endothelial Function and Acute Coronary Syndromes 9. Infection 10. Triggers to Acute Coronary Syndromes 11. Novel Risk Factors for ACS 12. What Cardiologists Need to Know about Depression III. Diagnosis 13. Clinical Recognition of Acute Coronary Syndromes 14. The Role of ECG, ECG Monitoring and Provocative Stress Testing in Acute Coronary Syndromes 15. Biochemical Markers of Myocardial Necrosis 16. Markers of a Thrombotic State 17. Markers of Inflammation 18. Angiographic Characterization of the Culprit Lesion in ACS 19. Nuclear Cardiology in Acute Coronary Syndromes 20. Echocardiography in Acute Coronary Syndromes 21. Cardiac Magnetic Resonance 22. Computed Tomography for Acute Coronary Syndromes 23. Emerging Diagnostic Procedures for Vulnerable Plaque 24. ACS in the Emergency Department: Diagnosis, Risk Stratification and Management 25. ACS in the CCU 26. Risk Stratification in Unstable Angina/Non-ST Elevation Myocardial Infarction IV. Special Subgroups 27. The Elderly, Woman and Patient with Diabetes 28. Coronary Artery Spasm 29. Cocaine and Other Environmental Causes of Acute Coronary Syndromes 30. The Patient with Chest Pain Despite Normal Coronary Angiography 31. The Patient with Disabling Angina Not Amenable to Revascularization (ECP, TMR, IABC, PMR, spinal chord stimulation) V. Pharmacologic Management 32. Nitrates and Nitric Oxide Donors 33. Beta-blockers and Calcium Channel Blockers (CCBs): Use in Acute Coronary Syndromes 34. ATP-sensitive Potassium Channels, Adenosine and Preconditioning 34. ATP-sensitive potassium channels, adenosine Preconditioning 35. Metabolic Interventions 36. Antiplatelet Therapy * Aspirin * The Combination Aspirin-Clopidogrel * Other ADP Antagonists * The GPIIb/IIIa Antagonists * New Antiplatelet Agents 37. Anticoagulants in Acute Coronary Syndromes 38. Anti-thrombotic Management 39. Treatment of Cardiovascular Inflammation 40. Acute Plaque Passivation and Endothelial Therapy 41. Perspective for Gene Therapy 42. Myocardial cell protection VI. Revascularization 43. Revascularization in Acute Coronary Syndromes: Which Patients and When? 44. Advantages and Hazard of Early Revascularization 45. New Revascularization Procedures, Surgical and Percutaneous 46. Cardiovascular Regeneration and Stem Cell Differentiation in Myocardial Ischemia 47. Pharmacological Revascularization VII. From the Acute to the Chronic Phase 48. Control of Risk Factors 49. Dietary Intervention in the Coronary Care Units and in Secondary Prevention VIII. Outlook to the Future 50. ACS: Outlook to the Future IX. Guidelines for Management 51. Guidelines for Management: AHA/ACC and ESC Task Forces
