Full Description
The new edition of this comprehensive text presents a complete guide to hematology, beginning with normal hematopoiesis and covering diseases of erythroid, myeloid, lymphoid and megakaryocytic origin. It also addresses complementary testing areas, such as flow cytometry, cytogenetics and molecular diagnostics. An excellent chapter on automated cell counting compares and contrasts major instruments. The easy-to-follow format promotes effortless teaching and learning, with colour figures organised as close to the citation as possible for easy reference. This full-colour edition is generously illustrated with high-quality photographs, drawings, and extensive full-color slides. It features case studies relevant to the topic in each chapter, follow-up questions at the end, useful chapter summaries, and much more. All-new information on molecular diagnostics and a completely revised section on hemostasis and thrombosis by George Fritsma bring the text up-to-date with current content. Readers will find all the essential content needed in a superb, quick-reference laboratory resource, as well as the pedagogy and accessible reading level that make it an ideal teaching textbook!
Contents
PART I: Introduction to Hematology * Safety in the Clinical Laboratory* Specimen Collection* Care and Use of the Microscope* Quality Control/Quality AssurancePART II: Hematopoiesis * Morphology and Function of Cellular Components* Hematopoietic Theory* Erythrocyte Production and Destruction* Erythrocyte Metabolism* Hemoglobin Metabolism* Iron Metabolism* Leukopoiesis* MegakaryopoiesisPART III: Routine Laboratory Testing of Blood Cells and Bone Marrow* Routine Testing in Hematology* Examination of the Peripheral Blood Smear* Introduction to Bone MarrowPART IV: Hematopathology: Erythrocyte Disorders* Anemias: Erythrocyte Disorders and Approach to Diagnosis* Disorders of Iron Metabolism* Disorders of Nuclear Development leading to Anemia* Bone Marrow Failure* Introduction to Increased Destruction of Erythrocytes* Intracorpuscular Defects leading to Erythrocyte Destruction* Extracorpuscular Defects leading to Increased Erythrocyte Destruction - Non-immune causes* Extracorpuscular Defects leading to Increased Erythrocyte Destruction - Immune causes* Structural Defects in Hemoglobin (Hemoglobinopathies)* ThalassemiasPART V: Non-Malignant Leukocyte Disorders * Qualitative Leukocyte Disorders* Quantitative Leukocyte DisordersPART VI: Ancillary Studies * Cytochemistry* Immunocytochemistry* Cytogenetics* Molecular DiagnosticsPART VII: Hematopathology: Malignant Disorders Of Leukocytes * Introduction to Leukocyte Neoplasia* Acute Leukemias* Chronic leukemias* Myeloproliferative Disorders* Lymphoproliferative Disorders* Myelodysplastic Syndromes* Treatment of Leukocyte NeoplasmsPART VIII: Hematology Instrumentation * Flow Cytometric Analysis* Cell Counting InstrumentationPART IX: Body Fluid Examination * Body FluidsPART X: Hemostasis and Thrombosis * Normal Hemostasis and Coagulation* Hemorrhagic Coagulation Disorders* Thrombosis Risk Testing* Quantitative Disorders of Platelets* Qualitative Disorders of Platelets* Evaluation of Hemostasis* Coagulation InstrumentationPART XI: Management * Management in the Hematology LaboratoryAppendix A: Answers to Review Questions
