Full Description
For 35 years, Thompson and Thompson Genetics in Medicine has been a favourite genetics textbook for medical students. This long-awaited sixth edition continues to provide a readable and understandable review of the basic principles of medical genetics, including recent advances in molecular genetics and the clinical applications of this new knowledge for the diagnosis and management of genetic disorders. Now brought completely up to date, this edition has been extensively revised and includes new information on developmental defects, genetics of complex diseases, genetics of cancer, molecular and biochemical basis of genetics, and the human genome project. It also features an all-new set of 29 clinical cases with colour photographs to assist students in relating basic genetics to clinical genetic disease. These cases will also help instructors integrate clinical material into their courses.
Contents
Introduction, Chromosomal Basis of Heredity, Structure and Function of Chromosomes and Genes, Tools of Human Molecular Genetics, Patterns of Single-gene Inheritance, Genetic Variation in Individuals: Mutation and Polymorphism, Genes in Population, Gene Mapping Clinical Cytogenetics, Sex Chromosomes and Their Abnormalities, The Molecular and Biochemical Basis of Genetic Disease: Hemoglobinopathies, Molecular and Biochemical Basis of Genetic Disease, Treatment and Gene Therapy, The Immune System, Genetics of Disorders with Multifactorial Inheritance, Genetics of Cancer, Genetic Aspects of Development, Clinical Genetics, Prenatal Diagnosis, Genetics and Society, Glossary
