Microbial Subversion of Host Cells (Society for General Microbiology Symposia)

Microbial Subversion of Host Cells (Society for General Microbiology Symposia)

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  • 製本 Hardcover:ハードカバー版/ページ数 300 p.
  • 言語 ENG
  • 商品コード 9780521829984
  • DDC分類 579

Full Description


Microbes have co-evolved with other organisms for eons, to the extent that some are so acquainted with host cell biology that they subvert key cellular processes with unrivalled precision. Pathogenic bacteria and viruses, for example, are extremely adept at intercepting host signal transduction pathways, re-routing protein traffic, remodelling the cytoskeleton and influencing host cell differentiation or death. Symbionts and commensal organisms, too, have evolved sophisticated strategies to derive benefit from the host environment without eliciting responses that compromise their viability. This volume reviews this exciting new discipline, reflecting both the recent explosion of knowledge and the wider insights into fundamental cellular processes that are provided. The authors, chosen for their contributions to the field, cover all the salient aspects using a range of model systems.

Contents

Preface; 1. The structure of the enteropathogenic Escherichia coli type III-secretion apparatus Elizabeth A. Creasey and Gad Frankel; 2. Vaccinia virus movement in cells Geoffrey L. Smith; 3. Induction of pro-inflammatory signals by Salmonella-epithelial cell interactions Abigail N. Blakey and Edouard E. Galyov; 4. Modulation of Toll-like receptor signalling by viruses Andrew Bowie; 5. Enteropathogenic Escherichia coli (EPEC) and its effector molecules Brendan Kenny and Jonathan Warawa; 6. Lipid-protein interactions in enveloped virus entry, protein traffic, and assembly Min Li, Andrei N. Vzorov, Armin Weidmann, Chinglai Yang and Richard W. Compans; 7. Legionella pneumophila: a model system to study bacterial modulation of phagosome transport Craig R. Roy; 8. Regulation of membrane fusion processes in eukaryotic cells: what can we learn from pathogenic mycobacteria? Jean Pieters; 9. Molecular and cellular mechanisms of action of the VacA and HP-NAP virulence factors of Helicobacter pylori Marina de Bernard and Cesare Montecucco; 10. Who is controlling the inflammatory response in shigellosis - bacteria or host? Jonathan D. Edgeworth and Philippe J. Sansonetti; 11. Cell death on demand: herpes simplex viruses and apoptosis Joshua Munger, Guoying Zhou and Bernard Roizman; 12. Apoptosis in Shigella and Salmonella infections Volker Brinkmann and Arturo Zychlinsky; 13. Setting up a nest and maintaining it: intracellular replication of Legionella pneumophila Ralph R. Isberg; 14. Entry of Listeria monocytogenes into mammalian cells: from cell biology to physiopathology P. Cossart; Index.