C型肝炎<br>Hepatitis C Virus : From Laboratory to Clinic

個数:

C型肝炎
Hepatitis C Virus : From Laboratory to Clinic

  • 提携先の海外書籍取次会社に在庫がございます。通常3週間で発送いたします。
    重要ご説明事項
    1. 納期遅延や、ご入手不能となる場合が若干ございます。
    2. 複数冊ご注文の場合、分割発送となる場合がございます。
    3. 美品のご指定は承りかねます。
  • 【入荷遅延について】
    世界情勢の影響により、海外からお取り寄せとなる洋書・洋古書の入荷が、表示している標準的な納期よりも遅延する場合がございます。
    おそれいりますが、あらかじめご了承くださいますようお願い申し上げます。
  • ◆画像の表紙や帯等は実物とは異なる場合があります。
  • ◆ウェブストアでの洋書販売価格は、弊社店舗等での販売価格とは異なります。
    また、洋書販売価格は、ご注文確定時点での日本円価格となります。
    ご注文確定後に、同じ洋書の販売価格が変動しても、それは反映されません。
  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 270 p.
  • 言語 ENG
  • 商品コード 9780521799591
  • DDC分類 616.3623

Full Description

Hepatitis C infects 170 million people worldwide, and has been labelled the 'silent epidemic' as a result of its concealed attack on the liver. This multidisciplinary overview covers basic concepts related to the discovery of the virus, development of serological and nucleic acid tests to detect infection, the structure of the virus genome, generation of virus gene products, and proposed replication scheme. It then goes on to introduce the epidemiology, transmission, pathogenesis of infection, the development of hepatocellular carcinoma associated with chronic virus infection, and current strategies for treatment. The book then discusses advances in cell culture systems, animal models of infection, and emerging treatments and vaccine development. Through its coverage of basic science, clinical consequences, and methods of research, this integrated and accessible account will be of immense value to biomedical scientists and clinicians alike, and a useful introduction for all those studying the virus and its effects.

Contents

Preface; Part I. Basic Principles: 1. Background; 2. The virus; 3. Epidemiology and transmission; 4. Natural history of infection; 5. Pathogenesis of infection; 6. HCV and hepatocellular carcinoma; 7. Extrahepatic sites for hepatatis C; 8. HCV and autoimmune diseases; 9. Clinical aspects of the disease; 10. Current therapeutic approaches; 11. NS5A and interferon resistance; Part II. Recent Advances: 12. Propagation of virus in culture; 13. Understanding the natural history of HCV; 14. HCV animal models; 15. Vaccine research; Part III. Experimental Approaches: 16. New systems to understand HCV biology; 17. New antiviral screening assays; 18. Antiviral gene therapy; Part IV. Protocols and Techniques: 19. Sample collection, preparation and storage; 20. HCV RNA in blood and tissue samples; 21. HCV RNA genotypes and quasispecies; 22. Replication of HCV in tissue culture; 23. NS3 protease, helicase and NTPase; 24. Characterization of NS5B; Part V. Outstanding Questions and Emerging Areas for Investigation; References; Index.