基本説明
最新分子生物学のテクニックで可能になった神経生物学における成果の最新情報をカバー
A thoroghly updated and revised edition of C. U. M. Smith's popular 1996 book. New Topics: genomics; ion channels; neural stem cells; gap junctions; channelopathies; cannabinoids; DNA-chips; and more.
Full Description
This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This "evodevo" (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology.
* Well known and widely used as a text throughout the UK, good reviews from students and lecturers.
* Good complement to Fundementals of Psychopharmacology by Brian Leonard.
This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists.
It is also a useful basic reference for university libraries.
Maurice Elphick, Queen Mary, University of London
"I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams."
Contents
Preface. Preface to the First Edition.
Preface to the Second Edition.
Introductory Orientation.
The Conformation of Informational Macromolecules.
Information Processing in Cells.
Molecular Evolution.
Manipulating Biomolecules.
Genomics.
Biomembranes.
G-protein-coupled Receptors.
Pumps.
Ligand-gated Ion Channels.
Voltage-gated Channels.
Resting Potentials and Cable Conduction.
Sensory Transduction.
The Action Potential.
The Neuron as a Secretory Cell.
Neurotransmitters and Neuromodulators.
The Postsynaptic Cell.
Developmental Genetics of the Brain.
Epigenetics of the Brain.
Memory.
Some Pathologies.
Appendix 1. Molecules and Consciousness.
Appendix 2. Units.
Appendix 3. Data.
Appendix 4. Genes.
Appendix 5. Physical Models of Ion Conduction and Gating.
Acronyms and Abbreviations.
Glossary.
Bibliography.
Index of Neurological Disease.
Index.
