Full Description
This volume will focus on and emphasise the clinical relevance of diabetic nephropathy, a relatively common problem of diabetes. It affects about one in three patients with Type 1 diabetes, and left untreated can lead to a progressive decline in renal function, accompanied by retinopathy and arterial hypertension, which, in turn, leads to cardiovascular disease - a common cause of death in these patients. Diabetic Nephropathy will also provide the reader with a solid grounding in current basic and clinical research.
Contents
List of Contributors.
Preface.
PART I: NATURAL COURSE, PATHOGENESIS, MORPHOLOGY AND GENETICS.
Diabetic Nephropathy--the Size of the Problem (E. Ritz & I. Rychlik).
Natural Course of Diabetic Nephropathy (C. Hasslacher).
Pathogenesis of Diabetic Nephropathy: Biochemical and Functional Alterations of Glomerular Basement Membrane and Mesangium (B. A. Yard et al.).
Pathogenesis of Diabetic Nephtopathy: Haemodynamic Alterations (H. J. G. Bilo et al.).
Renal Structural Damage in IDDM and NIDDM--Functional Relationships (R. Bilous).
Diabetic Nephropathy in Children and Adolescents (T. Danne et al.).
Genetic Predictors and Markers of Diabetic Nephropathy (R. Mangili).
PART II: CLINICAL PROBLEMS AND CONCOMITANT DISEASES.
Screening for and Diagnosis of Incipient Diabetic Nephropathy (IDN) in Diabetes (M. Ganz et al.).
Differential Diagnosis of Proteinuria in Diabetic Patients (D. Cordonnier et al).
Hypertension in Diabetic Nephropathy (C. Hasslacher).
Cardiovascular Complications in Proteinuric Diabetic Patients (P. Sawicki).
Lipid Disorders in Diabetic Nephropathy (C. Wanner et al.).
Eye Complications in Diabetic Nephropathy (M. Porta).
Pregnancy and Diabetic Nephropathy (A. Mackie).
PART III: TREATMENT AND PROGNOSIS.
Effect of Glycaemic Control in the Development and Progression of Diabetic Nephropathy (C. Hasslacher).
Blood Pressure Control in Hypertensive Diabetic Patients with Proteinuria (R. F. Schä fers et al.).
Early Antihypertensive Intervention in Diabetic Patients with Incipient Nephropathy (M. Marre et al.).
Dietary Modifications in Patients with Diabetic Nephropathy (M. Toeller & A. E. Buyken).
Training of Patients with Diabetic Nephropathy (B. Adam & C. Hasslacher).
Endstage Renal Failure in Diabetes Mellitus: Special Problems of Treatment and Monitoring (M. Zeier).
Prognosis of Patients with Diabetic Nephropathy (G. Biesenbach).
Index.
