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基本説明
The first textbook treatment of this essential technique, from biochemical principles underlying the technology through to discussion of methodology and a rigorous.
Full Description
This authoritative text begins with an introduction to basic microarray technology. The author then provides clear explanations of the conceptual and theoretical basis of this technology, followed by thorough and multi-disciplinary coverage of modern and emerging applications. The coverageincludes chapters on microarray informatics, gene expression profiling, genetic diagnostics, and novel microarray technologies.
Contents
Preface. Introduction to Microarray Analysis. Introduction to Chemistry. Basics of Biochemistry. Genes and Genomes. Microarray Surfaces. Targets and Probes. Microarray Manufacturing. Microarray Detection. Microarray Informatics. Methodological Architecture. Cleanroom Technology. Gene Expression Profiling. Genetic Screening and Diagnostics. Novel Microarray Technologies. Commercial Opportunities A to Z. Future Trends: Chips in the Clinics. Appendix A: Prefixes. Appendix B: Unit Abbreviations. Appendix C: Technical Abbreviations. Appendix D: Conversions. Appendix E: Nucleic Acid Molecular Weight Calculations. Appendix F: Microarray Spot Area Calculations. Appendix G: Microarray Fluor Density Calculations. Appendix H: Microarray Target Density Calculations. Appendix I: Microarray Web Sites. References. Glossary. Answers. Index.