不斉合成の原理と応用<br>Principles and Applications of Asymmetric Synthesis

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不斉合成の原理と応用
Principles and Applications of Asymmetric Synthesis

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  • 製本 Hardcover:ハードカバー版／ページ数 515 p.
  • 言語 ENG
  • 商品コード 9780471400271
  • DDC分類 547.2

基本説明

More than 450 reactions are covered.

Full Description

Asymmetric synthesis remains a challenge to practicing scientists as the need for enantiomerically pure or enriched compounds continues to increase. Over the last decade, a large amount of literature has been published in this field. Principles and Applications of Asymmetric Synthesis consolidates and evaluates the most useful methodologies into a one-volume resource for the convenience of practicing scientists and students.
Authored by internationally renowned scientists in the field, this reliable reference covers more than 450 reactions and includes important stoichiometric as well as catalytic asymmetric reactions. The first chapter reviews the basic principles, common nomenclature, and analytical methods, and the remainder of the book is organized according to reaction type. The text examines such topics as:

Carbon-carbon bond formations involving carbonyls, enamines, imines, and enolates

Asymmetric C-O bond formations including epoxidation, dihydroxylation, and aminohydroxylation

Asymmetric synthesis using the Diels-Alder reaction and other cyclizations

Applications to the total synthesis of natural products

Use of enzymes in asymmetric synthesis

Practicing chemists in the pharmaceutical, fine chemical, and agricultural professions as well as graduate students will find that Principles and Applications of Asymmetric Synthesis affords comprehensive and current coverage.

Contents

Preface.

Abbreviations.

Introduction.

-Alkylation and Catalytic Alkylation of Carbonyl Compounds.

Aldol and Related Reactions.

Asymmetric Oxidations.

Asymmetric Diels-Alder and Other Cyclization Reactions.

Asymmetric Catalytic Hydrogenation and Other Reduction Reactions.

Applications of Asymmetric Reactions in the Synthesis of Natural Products.

Enzymatic Reactions and Miscellaneous Asymmetic Syntheses.

Index.