基本説明
Includes an extensive update of the magnitude and nature of the epidemic, as well as regionally specific information on pathogenesis, diagnosis, epidemiology, treatment, pediatric infection, vaccine development, socioeconomic impact, and ethical considerations.
Full Description
This comprehensive reference book addresses the unique challenges facing many African nations as poor infrastructure and economics continue to obstruct access to advanced treatments and AIDS care training. It takes into account the context of settings with limited resources. Information on how to best utilize existing resources and prioritize scaling-up of infrastructure is a critical aspect of this book for those working in HIV/AIDS-related fields in Africa.
Contents
I: Pathogenesis. 1. Introduction: The Etiology of AIDS; M. Essex, S. Mboup. 2. The Molecular Virology of HIV-1; M. Montano, C. Williamson. 3. Immunopathogenesis of AIDS; L. Zijenah, D. Katzenstein. 4. Effect of Genetic Variation on HIV Transmission and Progression to AIDS; C.A. Winkle, S.J. O'Brien. 5. Biology of Human Immunodeficiency Virus Type 2 (HIV-2); P.J. Kanki, J-L. Sankalé, S. Mboup. 6. Simian Immunodeficiency Viruses and the Origin of HIVs; O.M. Diop, et al.
II: Detection and Monitoring of HIV Infection and Disease. 7. Serodiagnosis of HIV Infection; A. Guèye-Ndiaye. 8. Molecular Diagnosis of HIV Infection; B. Renjifo. 9. Monitoring HIV-1 Subtype Distribution; F.R. Barin, et al. 10. Monitoring Viral Load; P.J. Kanki, I. Mani. 11. Monitoring Immune Function; G. Biberfeld, E. Lyamuya.
III: Epidemiology. 12. The Epidemiology of HIV and AIDS; P. Piot, M. Bartos. 13. Transmission of HIV; S. Kristensen, et al. 14. Role of Sexually Transmitted Diseases in HIV Transmission; S.H. Kapiga, et al. 15. Mother-to-Child Transmission of HIV; A. Willoughby. 16. HIV-1 Subtypes and Recombinants; B. Renjifo, M. Essex. 17. Current Estimates and Projections for the Epidemic; K.A. Stanecki, N. Walker.
IV: Clinical Spectrum and Treatment of HIV-Related Diseases. 18. Clinical Diagnosis of AIDS and HIV-Related Diseases; C.L. Onen. 19. Antiretroviral Therapy in Resource-limited Settings; A. Amoroso, et al.20. HIV-1 Drug Resistance; M.A. Wainberg, B.G. Brenner. 21. Opportunistic Infections; R. Colebunders, et al. 22. Tuberculosis; R. Ridzon, H. Mayanga-Kizza. 23. HIV Infection and Cancer; R. Newton, et al. 24. Challenges and Opportunities for Nurses; S.D. Tlou. 25. Home-Based Care; Q.A. Karim, et al. 26. Nutrition and HIV Infection; A.K. Kiure, et al. 27. Access to HIV and AIDS Care; K. Ramanathan, et al.
V: Pediatric HIV Infection and Disease. 28. Diagnosis of Pediatric HIV Infection; C. Luo, B. Coulter. 29. Treatment of HIV in Children Using Antiretroviral Drugs; G.M. Anabwani, M.W. Kline. 30. Pediatric Opportunistic Infections; S. Lockman, K. McIntosh.
VI: Prevention of HIV Infection. 31. Male Condoms and Circumcision; R.L. Shapiro, S.H. Kapiga. 32. Female Condoms and Microbicides; E. Esu-Williams, K. Blanchard. 33. Behavioral Change: Goals and Means; P. Kebaabetswe, K. F. Norr. 34. Voluntary Counseling and Testing; E. Marum, et al. 35. Prevention of Perinatal Transmission of HIV; S. Le Coeur, M. Lallemant. 36. Prevention of Breast Milk Transmission of HIV: Balancing the Benefits and the Risks; R. Nduati, D. Mbori-Ngacha. 37. Postexposure Prophylaxis for Occupational Exposure and Sexual Assault; E. Bouvet, et al.
VII: Vaccine Development. 38. The Need for a Vaccine; S. Berkley. 39. HIV Vaccines: Design and Development; T-H Lee, V. Novitsky. 40.