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Full Description
A new edition of the popular introductory textbook for biochemistry and molecular biology. * Contains substantial new material * Contains even more of the clear colour diagrams Completely up to date. Elimination of inessential material has permitted full coverage of the areas of most current interest as well as coverage of essential basic material. Areas of molecular biology such as cell signalling, cancer molecular biology, protein targeting, proteasomes, immune system, eukaryotic gene control are covered fully, but still in a clear student friendly style. This makes the book suitable for the most modern type of courses. WHAT'S NEW New or completely re-written chapters - 2. Enzymes 3. The structure of proteins 4. The cell membrane - a structure depending only on weak forces 13. Strategies for metabolic control and their applications to carbohydrate and fat metabolism 17. Cellular disposal of unwanted molecules 23. Eukaryotic gene transcription and control 24. Protein synthesis, intracellular transport and degradation 25. How are newly synthesised proteins delivered to their correct destinations? - Protein targeting 26. Cell signalling 27. The immune system 30.
Molecular biology of cancer 33. The cytoskeleton, molecular motors and intracellular transport There are also several major insertions of new material, and minor editing to the rest of the book. SUPPORT MATERIAL ON THE WEB www oup.com/elliott * All the illustrations are available free for downloading * An introduction to the book by the authors * A detailed description of what's new to this edition (from August 2000) PLUS Student's Solutions Manual Instructor's Solutions Manual (tbc)
Contents
PART 1: INTRODUCTION TO THE CHEMICAL REACTIONS OF THE CELL; 1: Chemistry, energy, and metabolism; 2: Enzymes; PART 2: STRUCTURE OF PROTEINS AND MEMBRANES; 3: The structure of proteins; 4: The cell membrane; PART 3: METABOLISM; 5: Digestion and absorption of food; 6: Preliminary outline of fuel distribution and utilization by the different tissues of the body; 7: Biochemical mechanisms involved in food transport, storage, and mobilization; 8: Energy release from foodstuffs - a preliminary overview; 9: Glycolysis, the citric acid cycle, and the electron transport system: reactions involved in these pathways; 10: Energy release from fat; 11: A switch from catabolic to anabolic metabolism - first the synthesis of fat and related compounds in the body; 12: Synthesis of glucose in the body (gluconeogenesis); 13: Strategies for metabolic control and their application to carbohydrate and fat metabolism; 14: Why should there be an alternative pathway of glucose oxidation? - the pentose phosphate pathway; 15: Raising electrons of water back up the energy scale - photosynthesis; 16: Amino acid metabolism; 17: Cellular disposal of unwanted molecules; 18: Enzymic protective mechanisms in the body; 19: Nucleotide metabolism; PART 4: INFORMATION STORAGE AND UTILIZATION: 20: DNA - its structure and arrangement in cells; 21: DNA synthesis and repair; 22: Gene transcription - the first step in the mechanism by which genes direct protein synthesis; 23: Eukaryotic gene transcription and control; 24: Gene cloning, reProtein synthesis, intracellular transport, and degradation; 25: How are newly sythesised proteins delivered to their correct destinations - protein targeting; 26: Cell signalling; 27: The immune system; 28: Viruses and viroids; 29: Gene cloning, recombinant DNA technology, genetic engineering; 30: Molecular biology of cancer; PART 5: TRANSPORT OF OXYGEN AND CO2; 31: The red blood cell and role of hemoglobin; PART 6: MECHANICAL WORK BY CELLS; 32: Muscle contraction; 33: The cytoskeleton, molecular motors and intracellular transport; Answers to problems
