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基本説明
Out of Print
Full Description
The recent dramatic advances in imaging technologies have enabled researchers to build on the evidence obtained from lesion and behavioural studies to propose a new range of functions for the parahippocampal region. It is now possible to image the region in healthy human subjects and to define the pathological changes occurring during the early phases of a range of neurologic and psychiatric conditions. The results have uncovered evidence suggesting that the region plays an important role in the higher cognitive processes of learning and memory, and in specific brain diseases, including Alzheimer's disease, schizophrenia and epilepsy, as well as in the aging process itself. The Parahippocampal Region: Organization and Role in Cognitive Functions examines the architecture and activity of this section of the temporal lobe, describes the systems active in memory, perception and behaviour, and outlines the significance of its involvement in the progress of a range of disease states. It provides an overview of our current basic and clinical knowledge and a baseline for further expansion of the functional understanding of the region.
With contributions from an international team of authors this book will be of interest to neuroscientists, researchers and practitioners from the fields of neuropsychology, neurology and psychiatry, as well as to students from these disciplines.
Contents
SECTION 1; 1. The parahippocampal region: past, present and future; 2. Postnatal development of the human entorhinal cortex; SECTION 2; 3. Basic anatomy of the parahippocampal region in monkeys and rats; 4. Spotlight on the neurones (I): cell types, local connectivity, microcircuits, and distribution of markers; 5. Spotlight on the neurones (II): electrophysiology of the neurones in the perirhinal and entorhinal changes in firing patterns; 6. Communication between subregions of the parahippocampal region; 7. Gamma and ripple oscillations: functional indices of hippocampal-entorhinal interactions; 8. A simulation of parahippocampal and hippocampal structures guiding spatial navigation of a virtual rat in a virtual environment: a functional framework for theta theory; SECTION 3; 9. Memory representations in the parahippocampal region; 10. Cognitive electrophysiology of human parahippocampal structures; 11. Experimental lesions of the parahippocampal region in rats; 12. The role of perirhinal cortex in memory and perception: conjunctive representations for object identification; 13. Imaging cognitive function of the parahippocampal region; SECTION 4; 14. The human parahippocampal region in Alzheimer's disease, dementia, and ageing; 15. The parahippocampal region in schizophrenia; 16. The parahippocampal region in temporal lobe epilepsy
