Full Description
Paediatric Psychopharmacology: Principles in Practice is an authoritative and comprehensive text on the use of medication in the treatment of children and adolescents with serious neuropsychiatric disorders. This benchmark volume consists of 56 chapters written by internationally recognized leaders, and is divided into four interrelated sections. The first, Biological Bases of Pediatric Psychopharmacology, reviews key principles of neurobiology and the major psychiatric illnesses of childhood from a perspective rooted in developmental psychopathology. The second, Somatic Interventions, presents the major classes of psychiatric drugs, as well as complementary and alternative somatic interventions, such as electroconvulsive therapy (ECT), transcranial magnetic stimulation (rTMS), and naturopathic approaches. The third and longest section, Assessment and Treatment, starts with clinical assessment, diagnostic evaluation, and comprehensive treatment planning, and goes on to cover the evidence-based analysis of drug treatments for the major disorders.
Special populations (such as children with comorbid mental retardation, substance abuse or medical illness) are specifically discussed, and the coordination of their treatment with non-somatic therapies is explicitly addressed. The final section, Epidemiologic, Research and Methodological Considerations, deals with broad population-relevant topics such as regulation and policy, pharmacoepidemiology, and the critical importance of sound ethical principles for clinical investigation. The book concludes with an appendix on generic and commercial drug name equivalences, preparations and available dosages. This timely text is intended for child and adolescent psychiatrists, general and developmental paediatricians, family practitioners, general psychiatrists, and other mental health professionals who work with children and adolescents.
Contents
SECTION 1: BIOLOGICAL BASES OF PEDIATRIC PSYCHOPHARMACOLOGY; Part 1-A - Developmental Principles of Neurobiology and Psychopharmacology; 1. Overview of Brain Development; 2. Synaptic Function and Biochemical Neuroanatomy; 3. Mechanisms of Signal Transduction and Adaptation to Psychotropic Drug Action; 4. Pharmacokinetics I: Developmental Principles; 5. Pharmacokinetics II: Cytochrome P450-Mediated Interactions; Part 1-B - Genetic Principles; 6. Molecular Genetics; 7. Pharmacogenetics; Part 1-C - Developmental Psychopharmacology; 8. Neurobiology of Attention Regulation and its Disorders; 9. Neurobiology of Early-Life Stress and its Disorders; 10. Neurobiology of Early-Onset Mood Disorders; 11. Neurobiology of Early-Onset Anxiety Disorders; 12. Neurobiology of Obsessive-Compulsive Disorder; 13. Neurobiology of Tic Disorders, Including Tourette's Syndrome; 14. Neurobiology of Immune-Mediated Neuropsychiatric Disorders; 15. Neurobiology of Childhood Schizophrenia and Related Disorders; 16. Neurobiology of Affiliation: Implications for Autism Spectrum Disorders; 17. Neurobiology of Aggression; 18. Neurobiology of Eating Disorders; 19. Neurobiology of Substance Abuse Disorders; SECTION 2: SOMATIC INTERVENTIONS; Part 2-A - Psychotropic Agents; 20. Stimulants; 21. Adrenergic Agonists: Clonidine and Guanfacine; 22. Antidepressants I: Selective Serotonin Reuptake Inhibitors; 23. Antidepressants II: Tricyclic Agents; 24. Antidepressants III: Other Agents; 25. Mood Stabilizers: Lithium, Anticonvulsants and Others; 26. Antipsychotic Agents: Traditional and Atypical; 27. Anxiolytics: Benzodiazepines, Buspirone and Others; 28. Miscellaneous Compounds: Beta-Blockers, Opiate Antagonists and Others; Part 2-B - Other Somatic Interventions; 29. Complementary and Alternative Medicine in Pediatric Psychopharmacology; 30. Electroconvulsive Therapy and Transcranial Magnetic Stimulation; SECTION 3: ASSESSMENT AND TREATMENT; Part 3-A - General Principles; 31. Clinical Assessment of Children and Adolescents Treated Pharmacologically; 32. Clinical Instruments and Scales in Pediatric Psychopharmacology; 33. Thinking about Prescribing: The Psychology of Psychopharmacology; 34. Combining Pharmacotherapy and Psychotherapy: An Evidence-Based Approach; Part 3-B - Specific Disorders and Syndromes; 35. Attention-Deficit Hyperactivity Disorder; 36. Depressive Disorder; 37. Bipolar Disorder; 38. Anxiety Disorders; 39. Obsessive-Compulsive Disorders; 40. Tourette's Syndrome and Other Tic Disorders; 41. Early-Onset Schizophrenia; 42. Autistic and Other Pervasive Developmental Disorders; 43. Post-Traumatic Stress Disorder; 44. Eating Disorders; Part 3-C - Special Clinical Populations; 45. Substance Abusing Youths; 46. Individuals with Mental Retardation; 47. The Medically Ill Child or Adolescent; 48. Psychopharmacology During Pregnancy: Infant Considerations; 49. Psychopharmacological Treatment of Preschoolers; Part 3-D - Other Areas of Clinical Concern; 50. Agitation and Aggression; 51. Elimination Disorders; SECTION 4: EPIDEMIOLOGICAL, RESEARCH AND METHODOLOGICAL CONSIDERATIONS; 52. Pedatric Psychopharmacoepidemiology: Who is Prescribing? And For Whom, How and Why?; 53. Clinical Trials Methodology and Design Issues; 54. Regulatory Issues; 55. Ethical Issues in Research; 56. International Perspectives
