Full Description
This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, psychiatrists, and neurologists. Both authoritative and very readable, it has been thoroughly updated for each edition. In the eigth edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain and the growing recognition of nicotinic receptors in the brain and their possible involvement in Alzheimer's and Parkinson's disease. From reviews of the previous edition: "Recommended without reservation to students, physicians and scientists who seek a lucid survey of the biochemical basis of neuronal regulatory systems." New England Journal of Medicine "The best introductory text available for those who want to learn about the application of biochemical approaches to the study of neurotransmitter and drug actions in the nervous system." Brain "This now classic monograph remains a clear and concise guide...(It) should be mandatory reading for all medical students, psychiatry residents, graduate students in neuroscience and pharmacology, and is even useful for undergraduate students." Contemporary Psychiatry.
Contents
1. Introduction; 2. Cellular Foundations of Neuropharmacology; 3. Molecular Foundations of Neuropharmacology; 4. Receptors; 5. Modulation of Synaptic Transmission; 6. Amino Acid Transmitters; 7. Acetylcholine; 8. Norepinephrine and Epinephrine; 9. Dopamine; 10. Serotonin (5-Hydroxytryptamine), Histamine, and Adenosine; 11. Neuroactive Peptides; 12. Cellular Mechanisms in Learning and Memory; 13. Treating Neurological and Psychiatric Disorders
