Receptor and Ion-Channel Trafficking : Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels (Molecular and Cellular Neurobiology Series)

個数:

Receptor and Ion-Channel Trafficking : Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels (Molecular and Cellular Neurobiology Series)

  • 在庫がございません。海外の書籍取次会社を通じて出版社等からお取り寄せいたします。
    通常6~9週間ほどで発送の見込みですが、商品によってはさらに時間がかかることもございます。
    重要ご説明事項
    1. 納期遅延や、ご入手不能となる場合がございます。
    2. 複数冊ご注文の場合、分割発送となる場合がございます。
    3. 美品のご指定は承りかねます。
  • 【入荷遅延について】
    世界情勢の影響により、海外からお取り寄せとなる洋書・洋古書の入荷が、表示している標準的な納期よりも遅延する場合がございます。
    おそれいりますが、あらかじめご了承くださいますようお願い申し上げます。
  • ◆画像の表紙や帯等は実物とは異なる場合があります。
  • ◆ウェブストアでの洋書販売価格は、弊社店舗等での販売価格とは異なります。
    また、洋書販売価格は、ご注文確定時点での日本円価格となります。
    ご注文確定後に、同じ洋書の販売価格が変動しても、それは反映されません。
  • 製本 Hardcover:ハードカバー版/ページ数 236 p.
  • 言語 ENG
  • 商品コード 9780192632241
  • DDC分類 571.64

Full Description

A volume in the Molecular and Cellular Neurobiology series.

This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.

The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to cover ligand-gated ion channels with two chapters on acetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors.

Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.

Contents

ION CHANNELS ; 1. Voltage-gated sodium channels ; 2. The assembly and targeting of potassium channels ; 3. Assembly and targeting of voltage-dependent calcium channels ; ACETYLCHOLINE RECEPTORS ; 4. Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse ; 5. Assembly and targeting of neuronal nicotinic acetylcholine receptors ; AMINO ACID RECEPTORS ; 6. AMPA/kainate receptors ; 7. NMDA receptor targeting ; 8. Structure, assembly and targeting of glycine receptors ; 9. GABAA and GABAC receptors: regulation of assembly, localization, clustering and turnover