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Full Description
Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Structure, Replication and Evolution is the first volume of The Flaviviruses and presents the latest research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase.
Contents
Taxonomy of the virus family FlaviviridaeStructure and replicationMolecular Biology of the FlavivirusesFlavivirus Structure and Membrane FusionKunjin RNA replication and applications of Kunjin repliconsAntigenic structure of flavivirus Proteins5' and 3' non-coding regions in flavivirus RNAManipulation of Cell Surface Macromolecules by FlavivirusesFlavivirus evolutionOrigins, Evolution and vecto/host cp-adaptations within the genus FlavivirusMicroevolution and virulence of dengue viruses