Full Description
The seventh edition of this book is a comprehensive guide to biochemistry for medical students. Divided into six sections, the book examines in depth topics relating to chemical basics of life, metabolism, clinical and applied biochemistry, nutrition, molecular biology and hormones. New chapters have been added to this edition and each chapter includes clinical case studies to help students understand clinical relevance. A 274-page free booklet of revision exercises (9789350906378), providing essay questions, short notes, viva voce and multiple choice questions is included to help students in their exam preparation. Free online access to additional clinical cases, key concepts and an image bank is also provided. Key points *Fully updated, new edition providing students with comprehensive guide to biochemistry *Includes a free booklet of revision exercises and free online access *Highly illustrated with nearly 1500 figures, images, tables and illustrations *Previous edition published in 2010
Contents
SECTION AMedicine * Subcellular Organelles and Cell Membranes * Amino Acids: Structure and Properties * Proteins: Structure and Function * Enzymology: General Concepts and Enzyme Kinetics * Chemistry of Carbohydrates * Chemistry of Lipids SECTION B: General Metabolism * Overview of Metabolism *9 Major Metabolic Pathways of Glucose * Other Metabolic Pathways of Glucose * Metabolic Pathways of Other Carbohydrates * Metabolism of Fatty Acids * Cholesterol and Lipoproteins * MCFA, PUFA, Prostaglandins and Compound Lipids * General Amino Acid Metabolism (Urea Cycle, One Carbon Metabolism) * Simple, Hydroxy and Sulfur-containing Amino Acids (Glycine, Serine, Methionine, Cysteine) * Acidic, Basic and Branched Chain Amino Acids, (Glutamic acid, Aspartic acid, Glutamine, Asparagine, Lysine, Arginine, Nitric Oxide, Valine, Leucine, Isoleucine) * Aromatic Amino Acids (Phenylalanine, Tyrosine, Tryptophan, Histidine, Proline) and Amino Acidurias * Citric Acid Cycle * Biological Oxidation and Electron Transport Chain * Heme Synthesis and Breakdown * Hemoglobin (Structure, Oxygen and Carbon Dioxide Transport, Abnormal Hemoglobins) SECTION C: Clinical and Applied Biochemistry * Clinical Enzymology and Biomarkers * Regulation of Blood Glucose; Insulin and Diabetes Mellitus * Hyperlipidemias and Cardiovascular Diseases * Liver and Gastric Function Tests * Kidney Function Tests * Plasma Proteins * Acid-base Balance and pH * Electrolyte and Water Balance * Body Fluids (Milk, CSF, Amniotic Fluid, Ascitic Fluid) * Metabolic Diseases * Free Radicals and Antioxidants * Clinical Laboratory; Quality Control * General Techniques for Separation, Purification and Quantitation SECTION D: Nutrition * Fat Soluble Vitamins (A, D, E, K) * Water Soluble Vitamins - 1 (Thiamine, Riboflavin, Niacin, Pyridoxine, Pantothenic acid, Biotin) * Water Soluble Vitamins - 2 (Folic acid, Vitamin B12 and Ascorbic acid) * Mineral Metabolism and Abnormalities * Energy Metabolism and Nutrition * Detoxification and Biotransformation of Xenobiotics * Environmental Pollution and Heavy Metal Poisons SECTION E: Molecular Biology * Nucleotides: Chemistry and Metabolism * Deoxyribonucleic Acid: Structure and Replication * Transcription * Genetic Code and Translation * Control of Gene Expression * Recombinant DNA Technology and Gene Therapy * Molecular Diagnostics and Genetic Techniques SECTION F: Hormones * Mechanisms of Action of Hormones and Signaling Molecules * Hypothalamic and Pituitary Hormones * Steroid Hormones * Thyroid Hormones * Gut Hormones * Immunochemistry * Biochemistry of AIDS and HIV * Biochemistry of Cancer * Tissue Proteins in Health and Disease * Applications of Isotopes in Medicine * Signal Molecules and Growth Factors
