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基本説明
Gives a latest account with examples of key proteins in their biological context generously illustrated in full color to illuminate the structural principles in the text. Two entirely new chapters on 'Folding and Flexibility' and 'Fibrous Proteins'.
Full Description
Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.
Contents
PART 1 BASIC STRUCTURAL PRINCIPLES
1. The Building Blocks
2. Motifs of Protein Structure
3. α-Domain Structures
4. α/β Structures
5. β Structures
6. Folding and Flexibility
7. DNA Structures
PART 2 STRUCTURE, FUNCTION AND ENGINEERING
8. DNA Recognition in Procaryotes by Helix-Turn-Helix Motifs
9. DNA Recognition by Eukaryotic Transcription Factors
10. Specific Transcription Factors Belong to a Few Families
11. An Example of Enzyme Catalysis: Serine Proteinases
12. Membrane Proteins
13. Signal Transduction
14. Fibrous Proteins
15. Recognition of Foreign Molecules by the Immune System
16. The Structure of Spherical Viruses
17. Prediction, Engineering, and Design of Protein Structures
18. Determination of Protein Structures