基本説明
This work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; and more. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction.
Full Description
Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website.More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction.A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.
Contents
VOLUME IIntroduction: What Is Epilepsy?Overview: Epidemiology, Pathology, and GeneticsEpilepsy: Historical Perspectives NeuropathologyEPIDEMIOLOGYIncidence and PrevalenceThe Natural History and Prognosis of EpilepsyNEUROPATHOLOGYGeneral Neuropathology of EpilepsyHippocampal SclerosisGENETICSGenetic EpidemiologyEEG TraitsOverview: The Neurobiology of EpilepsyControl of Neuronal ExcitabilityExcitatory Synaptic TransmissionNeocortical Anatomy and PhysiologyThalamocortical Anatomy and PhysiologyGenetic Models of EpilepsySeizure Mechanisms and Vulnerability in the Developing BrainSECTION III PHENOMENOLOGYOverview: PhenomenologyEPILEPTIC SEIZURESSimple Motor SeizuresLimbic SeizuresEpileptic SpasmsSTATUS EPILEPTICUSGeneralized Convulsive Status EpilepticusAbsence Status EpilepticusMyoclonic Status EpilepticusEPILEPTIC DISORDERSClassification of the EpilepsiesOverview: Diagnostic EvaluationROUTINE INVESTIGATIONSHistory and Physical ExaminationEEGPhysiologic Basis of the Electroencephalogram and Local Field PotentialsIctal ElectroencephalogramPolygraphic RecordingsNEUROIMAGINGPositron Emission TomographyMagnetic Resonance SpectroscopyComputational AnatomyNEW DIRECTIONSSeizure PredictionMicrodialysisTranscranial Magnetic StimulationCellular Imaging of EpilepsyNEUROPSYCHOLOGICAL EVALUATIONLONG-TERM MONITORINGVOLUME IISECTION V GENERAL TREATMENT CONSIDERATIONSOverview: General Approaches to TreatmentGENERAL CONSIDERATIONSSTRATEGIES FOR PHARMACOTHERAPYSPECIAL THERAPEUTIC CONSIDERATIONSALTERNATIVE APPROACHESANTIEPILEPTIC DRUG DEVELOPMENTANTIEPILEPTIC DRUGSSECTION VII SURGICAL THERAPYCANDIDATE SELECTIONINVASIVE MONITORING TECHNIQUESFUNCTIONAL MAPPING TECHNIQUESTHERAPEUTIC SURGICAL PROCEDURESPOSTOPERATIVE FOLLOW-UPBIORHYTHMS AND THE AUTONOMIC NERVOUS SYSTEMCOMORBIDITYNEUROENDOCRINOLOGYVOLUME IIIPSYCHIATRIC ISSUESSOCIAL ISSUESSECTION X EPILEPSY SYNDROMESNEONATAL SYNDROMESNON AGE-RELATED AND SPECIAL SYNDROMESDISEASES ASSOCIATED WITH EPILEPSYSYSTEMIC DISTURBANCESNEUROLOGICAL DISTURBANCESPSYCHIATRIC DISTURBANCESSPECIALIZED CENTERS FOR EPILEPSYSubject Index
