Full Description
This work provides a comprehensive description of the molecular, chemical, and physical properties of proteins. It brings together in one authoritative resource coverage of all aspects of proteins-biosynthesis, evolution, dynamics ligand binding and catalysis, in YSI addition to their structures. The second edition has been thoroughly updated - especially in the area of protein biosynthesis - and features coverage of: developments in site-acted mutagenesis and protein engineering advances in the use of NMR to determine protein structure factors affecting the aqueous solubilities; of better understanding of the stabilities of folded conformations; how proteins interact with DNA; and progress in elucidating the mechanisms of protein degradation and turnover. This edition features end-of-chapter exercises and problems, many of which require the student to consult important contributions to the literature.
Contents
Chemical Properties of Polypeptides Biosynthesis of Proteins Evolutionary and Genetic Origins of Protein Sequences Physical Interactions that Determine the Properties of Proteins Conformational Properties of Polypeptide Chains The Folded Conformations of Globular Proteins Proteins in Solution and in Membranes Interactions with Other Molecules Enzyme Catalysis Degradation Appendix: References to Protein Structures Determined Crystallographically to High Resolution
