基本説明
医薬品の合成研究において蓄積されてきた。合成法、分類、化学データなどの情報を使いやすくまとめたレファレンス。ＷＨＯ必須医薬品リスト中に含まれるジェネリック医薬品を中心に取り上げている。
Provides a brief description of methods of synthesis activity and implementation of all drug types. Includes synonyms. Includes over 2300 references. Contents- General Anesthetics; Local Anesthetics; Analgesics; Hypnotis and Sedatives; Antiolitics(Tranquilizers); Antipsycotics(Neuroleptics); Antidepressants; and more.
Full Description
Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs.This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind - to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry.
Contents
1. General Anesthetics 2. Local Anesthetics 3. Analgesics 4. Hypnotics and Sedatives 5. Anxiolitics (Tranquilizers) 6. Antipsycotics (Neuroleptics) 7. Antidepressants 8. Central Nervous System Stimulants 9. Antiepileptics 10. Anti-Parkinson Drugs 11. Adrenegic (Sympatomimetic) Drugs 12. Adrenoblocking Drugs 13. Cholinomimetics 14. Anticholinergic Drugs 15. Muscle Relaxants 16. Antihistamine Drugs 17. Cardiac Glycosides and Other Inotropes 18. Drugs for Tachyarrhytmias 19. Antianginal Drugs 20. Agents Used in Hyperlipoproteinemia 21. Diuretics 22. Antihypertensive Drugs 23. Drugs for Treating of Pulmonary Diseases 24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics 25. Thyroid and Parathyroid Drugs 26. Insulin and Synthetic Hypoglycemic Agents 27. Corticosteroids 28. Female Sex Hormones 29. Male Sex Hormones and Anabolics 30. Antineoplastic Agents 31. Immunopharmacologic Drugs 32. Antibiotics 33. Antimicrobials 34. Antimicobacterials 35. Antifungal Drugs 36. Antiviral Drugs 37. Antiprotozoal Drugs 38. Antihelmint Drugs
