Full Description
Apprentices to Genius: A tribute to Solomon H. Snyder, a volume in the Advances in Pharmacology series, presents a tribute to Dr. Solomon H. Snyder, highlighting chapters submitted from a broad range of his students. It covers many different areas of neuroscience and pharmacology, with this volume exploring how receptor binding and drug discovery, the emerging role of glutamate in the pathophysiology of mental illness, nitric oxide signaling in neurodegeneration and cell death, carboxypeptidase E and the identification of novel neuropeptides as potential therapeutic targets, the regulation of mitochondrial functions by TSPO, clozapine and its translational investigation, and more.
Contents
1. Multiple Pathways Mediate MicroRNA Degradation: Focus on the Translin/Trax RNase ComplexJay M. Baraban, Aparna Shah and Xiuping Fu2. Receptor Binding Assays and Drug DiscoveryDavid B. Bylund and Sam J. Enna3. The Role of Serine Racemase in the Pathophysiology of Brain DisordersJoseph T. Coyle and Darrick T. Balu4. Nitric Oxide Signaling in Neurodegeneration and Cell DeathTed M. Dawson and Valina L. Dawson5. Carboxypeptidase E and the Identification of Novel Neuropeptides as Potential Therapeutic TargetsLloyd D. Fricker6. Regulation of Mitochondrial, Cellular, and Organismal Functions by TSPOMoshe Gavish and Leo Veenman7. Unique Effects of Clozapine: A Pharmacological PerspectiveJibran Y. Khokhar, Angela M. Henricks, Emily Kirk and Alan I. Green8. Imaging Translocator Protein as a Biomarker of Neuroinflammation in DementiaWilliam C. Kreisl, Ioline D. Henter and Robert B. Innis9. RNA-Based Fluorescent Biosensors for Detecting Metabolites In Vitro and in Living CellsSamie R. Jaffrey10. Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine ActionCaline S. Karam and Jonathan A. Javitch11. Anti-NMDA Receptor Encephalitis: Clinical Features and Basic MechanismsDavid R. Lynch, Amy Rattelle, Yi Na Dong, Kylie Roslin, Amy J. Gleichman and Jessica A. Panzer12. Mu Opioid Pharmacology: 40 Years to the Promised LandGavril W. Pasternak13. Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5A. Harrison Brody and Stephen M. Strittmatter14. The Neurobiology of d-Serine SignalingHerman Wolosker
