Full Description
This volume covers the latest advances in the mechanisms of pathogenesis of the HIV-1 virus on target cells. Its companion volume, Advances in Pharmacology 56, shows how new developments in understanding the virus translate to the clinical setting.
Contents
HIV-1 RNA PackagingStructure and Function of the HIV Envelope Glycoprotein as Entry Mediator, Vaccine Immunogen, and Target for InhibitorsHIV-1 Reverse Transcription: Close Encounters Between the Viral Genome and a Cellular tRNATranscription of HIV: Tat and Cellular ChromatinPosttranscriptional Control of HIV-1 and Other Retroviruses and Its Practical ApplicationsHIV Accessory Genes Vif and VpuInteractions of HIV-1 Viral Protein R with Host Cell ProteinsHIV-1 Protease: Structure, Dynamics, and InhibitionProperties, Functions, and Drug Targeting of the Multifunctional Nucleocapsid Protein of the Human Immunodeficiency VirusHuman Immunodeficiency Virus Type 1 Assembly, Release, and MaturationRole of Nef in HIV-1 Replication and PathogenesisTreatment Implications of the Latent Reservoir for HIV-1RNA Interference and HIV-1