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Full Description
The book reviews the literature on the regulation of NADPH oxidase, which is controversial in many areas, and refers specifically to relevant publications from the past 4 years. Main topics are catalytical properties, cofactor requirements and structural components of NADPH oxidase, activation of NADPH oxidase, inhibition of NADPH oxidase, reconstitution and regulation of NADPH oxidase activity in cell-free systems, and pathology of NADPH oxidase. This monograph on biochemistry and physiology is intended for research clinicians and biochemists in the above fields.
Contents
Introduction. NADPH oxidase: A superoxide-forming enzyme system. Activation od NADPH oxidase. Inhibition of NADPH oxidase. Reconstitution and regulation of NADPH oxidase activity in cell-free systems. Pathology of NADPH oxidase. Age- and sex-related alterations of the activity of NADPH oxidase. Concluding remarks.