ヒトの分子病理学 Molecular Pathology : The Molecular Basis of Human Disease

Coleman, William B. (EDT)/ Tsongalis, Gregory J. (EDT)

Academic Pr（2009/03発売）

• 製本 Hardcover:ハードカバー版／ページ数 636 p.
• 言語 ENG
• 商品コード 9780123744197
• DDC分類 616.07

基本説明

Explains the practice of "molecular medicine" and the translational aspects of molecular pathology.

Full Description

Molecular Pathologycurrent and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows.

Contents

PART IMolecular Mechanisms of Cell DeathAcute and Chronic InflammationInfection and Host ResponseNeoplasiaPART II: Concepts in Molecular Biology and GeneticsBasic Concepts in Human Molecular GeneticsThe Human Genome: Implications for the Understanding of Human DiseaseThe Human Transcriptome: Implications for the Understanding of Human DiseaseThe Human Epigenome: Implications for the Understanding of Human DiseaseThe Human Proteome: Implications for the Understanding of Human DiseaseIntegrative Systems Biology: Implications for the Understanding of Human DiseasePART III:Principles and Practice of Molecular PathologyPathology: The Clinical Description of Human DiseaseMolecular Pathogenesis: The Biological Basis of Human DiseaseIntegration of Molecular and Cellular PathogenesisPART IV: Molecular Pathology of Human Disease Molecular Basis of Cardiovascular DiseaseMolecular Basis of Hemostatic and Thrombotic DiseasesMolecular Basis of Lymphoid and Myeloid DiseasesMolecular Basis of Diseases of ImmunityMolecular Basis of Pulmonary DiseaseMolecular Basis of Diseases of the Gastrointestinal TractMolecular Basis of Liver DiseaseMolecular Basis of Diseases of the Exocrine PancreasMolecular Basis of Diseases of the Endocrine SystemMolecular Basis of Gynecologic Diseases Molecular Basis of Prostate DiseaseMolecular Basis of Breast DiseaseMolecular Basis of Skin DiseaseMolecular Basis of Diseases of the Nervous SystemPART V: Practice of Molecular MedicineMolecular Diagnosis of Human DiseaseMolecular Assessment of Human Disease in the Clinical LaboratoryPharmacogenomics and Personalized Medicine in the Treatment of Human Disease