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Full Description
This updated and revised edition delineates the basic concepts and fundamental principles needed to grasp current issues in modern toxicology. In addition, new contributions help to redefine the book's scope and coverage, and illuminate new and emerging areas of toxicologic interest. True to the tradition of previous editions, the current work balances its broad coverage with a basic, fundamental, mechanistic approach to toxicology. The text is organized and presented in a logical progression of general information (general principles) to specific information on organ system toxicology, specific agent toxicology and environmental toxicology.
Contents
Part 1 General principles of toxicologytoxicology; principles of toxicology; mechanisms of toxicology; biotransformation of toxicants; chemical carcinogenesis; genetic toxicology; teratogens. Part 2 System toxicology: toxic responses of the blood; toxic responses of the immune system; toxic responses of the liver; toxic responses of the kidney; responses of the respiratory system to toxic agents; toxic responses of the nervous system; toxic responses of the heart and vascular system; toxic responses of the skin; toxic responses of the reproductive system; toxic responses of the eye; toxic responses of the endocrine system. Part 3 Toxic agents: toxic effects of pesticides; toxic effects of metals; toxic effects of solvents and vapours; toxic effects of radiation and radioactive materials; toxic effects of animal toxins; toxic effects of plant toxins. Part 4 Environmental toxicology: food additives and contaminants; air pollutants; water and soil pollutants. Part 5 Applications of toxicology; analytical/forsenic toxicology; clinical toxicology; occupational toxicology; regulatory toxicology; risk assessment.
